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小细胞肺癌患者的健康相关生活质量:随机对照试验中报告方法和临床问题的系统评价。

Health-related quality of life in small-cell lung cancer: a systematic review on reporting of methods and clinical issues in randomised controlled trials.

机构信息

Quality of Life Department, EORTC Headquarters, Brussels, Belgium.

Quality of Life Department, EORTC Headquarters, Brussels, Belgium.

出版信息

Lancet Oncol. 2014 Feb;15(2):e78-89. doi: 10.1016/S1470-2045(13)70493-5.

DOI:10.1016/S1470-2045(13)70493-5
PMID:24480558
Abstract

Small-cell lung cancer represents about 15% of all lung cancers; increasingly, randomised controlled trials of this disease measure the health-related quality of life of patients. In this Systematic Review we assess the adequacy of reporting of health-related quality-of-life methods in randomised controlled trials of small-cell lung cancer, and the potential effect of this reporting on clinical decision making. Although overall reporting of health-related quality of life was acceptable, improvements are needed to optimise the use of health-related quality of life in randomised controlled trials.

摘要

小细胞肺癌约占所有肺癌的 15%;越来越多的此类疾病的随机对照试验开始衡量患者的健康相关生活质量。在本次系统性综述中,我们评估了小细胞肺癌随机对照试验中健康相关生活质量方法报告的充分性,以及这种报告对临床决策的潜在影响。尽管健康相关生活质量的总体报告是可以接受的,但仍需要改进,以优化健康相关生活质量在随机对照试验中的使用。

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