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胸腰椎脊柱肿瘤的治疗。

Treatment of tumors of the thoracic and lumbar spinal column.

作者信息

O'Neil J, Gardner V, Armstrong G

机构信息

Division of Orthopaedic Surgery, University of Ottawa, Ottawa Civic Hospital, Ontario, Canada.

出版信息

Clin Orthop Relat Res. 1988 Feb;227:103-12.

PMID:2448075
Abstract

From December 1981 to February 1986, 33 patients with tumorous conditions of the spine were treated with anterior, posterior, or combined anterior and posterior surgical techniques. Breast metastases were by far the most common condition, accounting for more than 51% of patients with metastatic spinal disease. The surgeon treating tumorous conditions of the spine must be aware that, to date, the treatment is palliative only. The goals of the surgery and treatment are to reduce pain, preserve or improve neurologic function, and allow early mobilization. Survival overall averaged 9.1 months. Of the 14 patients who had anterior decompression alone, average survival time was 9.9 months. The 14 patients who had posterior procedures had an average survival time of 11.9 months. Five patients treated with combined anterior and posterior procedures survived 9.6 months. Fifteen patients with multiple-level spinal involvement survived 7.9 months, compared with 12.9 months for the 18 patients with single-level spinal involvement. Aggressive surgical treatment definitely improves the quality of life of patients with cord compression or unstable spinal segments secondary to bony destruction. An aggressive approach is indicated because it permits most patients to spend the remainder of their lives relatively pain-free and with intact spinal cord function.

摘要

1981年12月至1986年2月,33例脊柱肿瘤患者接受了前路、后路或前后联合手术治疗。乳腺癌转移是迄今为止最常见的情况,占转移性脊柱疾病患者的51%以上。治疗脊柱肿瘤疾病的外科医生必须意识到,迄今为止,治疗仅为姑息性治疗。手术和治疗的目标是减轻疼痛、保留或改善神经功能,并允许早期活动。总体生存期平均为9.1个月。仅接受前路减压的14例患者,平均生存时间为9.9个月。接受后路手术的14例患者,平均生存时间为11.9个月。接受前后联合手术治疗的5例患者存活了9.6个月。15例多节段脊柱受累患者存活了7.9个月,而18例单节段脊柱受累患者存活了12.9个月。积极的手术治疗肯定能改善因骨质破坏继发脊髓压迫或脊柱节段不稳定患者的生活质量。采取积极的治疗方法是有必要的,因为它能使大多数患者在余生中相对无痛且脊髓功能完好。

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