Hagenmüller F, Sander C, Sander R, Ries G, Classen M
Technische Universität München, II. Medizinische Klinik und Poliklinik.
Endoscopy. 1987 Nov;19 Suppl 1:16-8. doi: 10.1055/s-2007-1018302.
The combination of laser and endoluminal 192-iridium irradiation for the palliation of malignancies of the esophagus and the cardia was introduced to overcome the short-term effect of laser treatment alone. On the basis of early experience, this method would seem to prolong the effect of laser treatment alone, and is associated with a low risk of complications. However, the initial optimistic results, claiming permanent relief of dysphagia in 80% of the patients, cannot be reproduced under prospective conditions. The combination of laser and 192-iridium irradiation with other palliative methods, such as external radiation treatment and/or chemotherapy is feasible, and remains to be studied in a comparative way.
为克服单纯激光治疗的短期效果，引入了激光与腔内192铱照射相结合的方法来缓解食管癌和贲门癌。根据早期经验，这种方法似乎能延长单纯激光治疗的效果，且并发症风险较低。然而，最初声称80%的患者吞咽困难得到永久性缓解的乐观结果，在前瞻性条件下无法重现。激光与192铱照射与其他姑息治疗方法（如外照射治疗和/或化疗）相结合是可行的，仍有待进行比较研究。
