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激光与腔内铱放射治疗对梗阻性食管癌和贲门癌的姑息治疗

Palliation of obstructive oesophageal and cardial carcinomas with laser and endoluminal iridium radiation.

作者信息

Hagenmüller F, Sander C, Sander R, Ries G, Classen M

出版信息

Baillieres Clin Gastroenterol. 1987 Oct;1(4):917-22. doi: 10.1016/0950-3528(87)90027-3.

DOI:10.1016/0950-3528(87)90027-3
PMID:2452663
Abstract

The combination of laser with endoluminal 192-iridium radiation for the palliation of malignancies of the oesophagus and the cardia has been introduced to overcome the short-lived effect of laser treatment alone. Concluding from early experience, this method seems to prolong the effect of laser treatment alone, with a low risk of complications. However the initial optimistic results, claiming a permanent relief of dysphagia in 80% of the patients, cannot be reproduced under prospective conditions. The combination of laser and 192-iridium radiation with other palliative methods, such as external radiation and/or chemotherapy is feasible and remains to be studied in a comparative way.

摘要

为克服单纯激光治疗效果短暂的问题,已引入激光与腔内192铱放射相结合的方法来缓解食管和贲门恶性肿瘤。根据早期经验推断,该方法似乎能延长单纯激光治疗的效果,且并发症风险较低。然而,最初声称80%的患者吞咽困难得到永久缓解的乐观结果,在前瞻性条件下无法重现。激光与192铱放射相结合以及与其他姑息治疗方法(如外照射和/或化疗)联合使用是可行的,仍有待进行比较研究。

相似文献

1
Palliation of obstructive oesophageal and cardial carcinomas with laser and endoluminal iridium radiation.激光与腔内铱放射治疗对梗阻性食管癌和贲门癌的姑息治疗
Baillieres Clin Gastroenterol. 1987 Oct;1(4):917-22. doi: 10.1016/0950-3528(87)90027-3.
2
Laser and endoluminal 192-iridium radiation.激光和腔内192铱放射治疗。
Endoscopy. 1987 Nov;19 Suppl 1:16-8. doi: 10.1055/s-2007-1018302.
3
Laser augmented by brachytherapy versus laser alone in the palliation of adenocarcinoma of the oesophagus and cardia: a randomised study.近距离放射治疗联合激光与单纯激光治疗缓解食管和贲门腺癌的随机研究
Gut. 2002 Feb;50(2):224-7. doi: 10.1136/gut.50.2.224.
4
[Palliative treatment of malignant stenoses of the esophagus and cardia: laser therapy versus laser + high-dose-rate Iridium 192 afterloading therapy. A prospective randomized study].[食管癌和贲门癌恶性狭窄的姑息治疗:激光治疗与激光+高剂量率铱192后装治疗。一项前瞻性随机研究]
Strahlenther Onkol. 1989 Aug;165(8):584-6.
5
Laser and brachytherapy in the palliation of adenocarcinoma of the oesophagus and cardia.激光和近距离放射疗法用于缓解食管癌和贲门腺癌
Gut. 1996 Nov;39(5):726-31. doi: 10.1136/gut.39.5.726.
6
Prospective randomized clinical trial comparing brachytherapy and laser photoablation for palliation of esophageal cancer.比较近距离放射疗法和激光光凝术缓解食管癌的前瞻性随机临床试验。
J Thorac Cardiovasc Surg. 1992 Jul;104(1):173-8; discussion 178-9.
7
Radiation enhancement of laser palliation for malignant dysphagia: a pilot study.激光缓解恶性吞咽困难的放射增强作用:一项初步研究。
Gut. 1992 Dec;33(12):1597-601. doi: 10.1136/gut.33.12.1597.
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[A therapeutic concept for the treatment of inoperable esophageal carcinoma].[一种治疗不可切除食管癌的治疗理念]
Strahlenther Onkol. 1990 Apr;166(4):247-50.
9
[Palliative treatment of esophageal and cardial carcinoma].
Minerva Chir. 1999 Oct;54(10):647-55.
10
[Laser and afterloading therapy: esophageal cancer].
Langenbecks Arch Chir Suppl II Verh Dtsch Ges Chir. 1990:185-91.

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