Hagenmüller F, Sander C, Sander R, Ries G, Classen M
Baillieres Clin Gastroenterol. 1987 Oct;1(4):917-22. doi: 10.1016/0950-3528(87)90027-3.
The combination of laser with endoluminal 192-iridium radiation for the palliation of malignancies of the oesophagus and the cardia has been introduced to overcome the short-lived effect of laser treatment alone. Concluding from early experience, this method seems to prolong the effect of laser treatment alone, with a low risk of complications. However the initial optimistic results, claiming a permanent relief of dysphagia in 80% of the patients, cannot be reproduced under prospective conditions. The combination of laser and 192-iridium radiation with other palliative methods, such as external radiation and/or chemotherapy is feasible and remains to be studied in a comparative way.
为克服单纯激光治疗效果短暂的问题,已引入激光与腔内192铱放射相结合的方法来缓解食管和贲门恶性肿瘤。根据早期经验推断,该方法似乎能延长单纯激光治疗的效果,且并发症风险较低。然而,最初声称80%的患者吞咽困难得到永久缓解的乐观结果,在前瞻性条件下无法重现。激光与192铱放射相结合以及与其他姑息治疗方法(如外照射和/或化疗)联合使用是可行的,仍有待进行比较研究。