Bush Larry M, Urrutia Jose G, Rodriguez Eduardo A, Perez Maria T
Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL, USA University of Miami-Miller School of Medicine, JFK Medical Center, Palm Beach County, FL, USA
Internal Medicine, University of Miami-Miller School of Medicine, JFK Medical Center, Palm Beach County, FL, USA.
J Int Assoc Provid AIDS Care. 2015 Nov-Dec;14(6):482-90. doi: 10.1177/2325957414520981. Epub 2014 Jan 30.
Despite treatment with potent and effective combination antiretroviral medications, the incidence of non-Hodgkin lymphoma (NHL) in the population living with HIV/AIDS remains significantly higher than that in noninfected individuals. The majority of the HIV-infected patients with NHL present with advanced stage extranodal disease of the B-cell phenotype. Lymphomas are the second most common tumors involving the heart in HIV-infected patients. Although the heart may serve as the primary focus of the lymphoma, in most HIV-related cases, cardiac lymphomatous involvement is part of a metastatic process that originated elsewhere.
尽管使用了强效且有效的抗逆转录病毒联合药物进行治疗，但艾滋病毒/艾滋病感染者中非霍奇金淋巴瘤（NHL）的发病率仍显著高于未感染者。大多数感染艾滋病毒的NHL患者表现为B细胞表型的晚期结外疾病。淋巴瘤是艾滋病毒感染者中累及心脏的第二常见肿瘤。虽然心脏可能是淋巴瘤的主要发病部位，但在大多数与艾滋病毒相关的病例中，心脏淋巴瘤受累是起源于其他部位的转移过程的一部分。
