Gal Asaf, Marom Shimon
The Interdisciplinary Center for Neural Computation (ICNC), The Hebrew University, Jerusalem, Israel and Network Biology Research Laboratories, Lorry Lokey Interdisciplinary Center for Life Sciences and Engineering, Technion, Haifa, Israel.
Network Biology Research Laboratories, Lorry Lokey Interdisciplinary Center for Life Sciences and Engineering, Technion, Haifa, Israel and Department of Physiology, Faculty of Medicine, Technion, Haifa, Israel.
Phys Rev E Stat Nonlin Soft Matter Phys. 2013 Dec;88(6):062717. doi: 10.1103/PhysRevE.88.062717. Epub 2013 Dec 18.
We present experimental and theoretical arguments, at the single-neuron level, suggesting that neuronal response fluctuations reflect a process that positions the neuron near a transition point that separates excitable and unexcitable phases. This view is supported by the dynamical properties of the system as observed in experiments on isolated cultured cortical neurons, as well as by a theoretical mapping between the constructs of self-organized criticality and membrane excitability biophysics.
我们在单神经元水平上提出了实验和理论依据，表明神经元反应波动反映了一个将神经元定位在可兴奋和不可兴奋阶段分隔的转变点附近的过程。在分离培养的皮层神经元实验中观察到的系统动力学特性，以及自组织临界性结构与膜兴奋性生物物理学之间的理论映射，都支持了这一观点。
