University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Zatisi 728/II, 389 25 Vodnany, Czech Republic.
University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Zatisi 728/II, 389 25 Vodnany, Czech Republic.
Sci Total Environ. 2014 Jul 15;487:681-7. doi: 10.1016/j.scitotenv.2013.12.091. Epub 2014 Jan 30.
The goal of this study was to assess the bioavailable concentrations of analgesics, psycholeptics, antidepressants and illicit drugs in the surface waters of the Czech Republic. All of the sampling sites are located within the most important water quality monitoring profiles at the Czech Hydrometeorological Institute. The total concentrations of the compounds ranged from 463 to 6,447 ng POCIS(-1) (Polar Organic Chemical Integrative Sampler). Carbamazepine (196-2,690 ng POCIS(-1)) and tramadol (160-2,250 ng POCIS(-1)) were the most abundant compounds at every site. The most polluted sites were those that received communal wastewater effluent and had a low dilution factor (ratio of wastewater effluent and river flow). The aqueous concentrations of the target compounds were estimated using sampling rate values obtained during a field calibration experiment. Patterns in the aqueous concentrations of the compounds (after back calculation from POCIS extracts) and the POCIS concentrations are different, possibly leading to discrepancies between the toxicity assessments conducted using POCIS extracts and those conducted using grab samples of water from the same location.
本研究旨在评估捷克共和国地表水中的镇痛剂、精神药物、抗抑郁药和非法药物的生物可利用浓度。所有采样点均位于捷克水文气象研究所最重要的水质监测剖面内。化合物的总浓度范围为 463 至 6,447 ng POCIS(-1)（极性有机化学综合采样器）。卡马西平（196-2,690 ng POCIS(-1)）和曲马多（160-2,250 ng POCIS(-1)）是每个采样点最丰富的化合物。受公共废水和低稀释因子（废水和河流流量的比例）影响的污染最严重的采样点。使用现场校准实验中获得的采样率值来估算目标化合物在水中的浓度。化合物在水中的浓度模式（从 POCIS 提取物反向计算）和 POCIS 浓度不同，这可能导致使用 POCIS 提取物进行的毒性评估与在同一地点采集的水样进行的毒性评估之间存在差异。
