Timpe L C, Schwarz T L, Tempel B L, Papazian D M, Jan Y N, Jan L Y
Howard Hughes Medical Institute, University of California, San Francisco 94143.
Nature. 1988 Jan 14;331(6152):143-5. doi: 10.1038/331143a0.
The Shaker gene of Drosophila melanogaster encodes a potassium-selective ion channel, the 'A' channel, or one of its subunits. A single Shaker messenger RNA species suffices to direct the synthesis of functional A channels in Xenopus oocytes. Physiological characteristics of the A currents induced by two different mRNA species are compared.
果蝇的震颤基因编码一种钾选择性离子通道,即“A”通道,或其亚基之一。单个震颤信使核糖核酸种类足以指导非洲爪蟾卵母细胞中功能性A通道的合成。比较了由两种不同信使核糖核酸种类诱导的A电流的生理特性。