果蝇中多个钾离子通道组件是由Shaker基因座的可变剪接产生的。
Multiple potassium-channel components are produced by alternative splicing at the Shaker locus in Drosophila.
作者信息
Schwarz T L, Tempel B L, Papazian D M, Jan Y N, Jan L Y
机构信息
Howard Hughes Medical Institute, University of California, San Francisco 94143.
出版信息
Nature. 1988 Jan 14;331(6152):137-42. doi: 10.1038/331137a0.
DOI:10.1038/331137a0
PMID:2448635
Abstract
At least four probable components of potassium channels are encoded at the Drosophila Shaker locus, by a family of alternatively spliced transcripts. Alternative splicing may provide one mechanism of generating the remarkable diversity of potassium channels.
摘要
果蝇的Shaker基因座通过一个可变剪接转录本家族编码钾通道的至少四个可能的组成部分。可变剪接可能是产生钾通道显著多样性的一种机制。
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