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抑郁负担与腰椎管狭窄症患者较差的手术结果相关:一项5年随访研究。

Depressive burden is associated with a poorer surgical outcome among lumbar spinal stenosis patients: a 5-year follow-up study.

作者信息

Pakarinen Maarit, Vanhanen Susanna, Sinikallio Sanna, Aalto Timo, Lehto Soili M, Airaksinen Olavi, Viinamäki Heimo

机构信息

Department of Psychiatry, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland.

Department of Physical and Rehabilitation Medicine, Mikkeli Central Hospital, Mikkeli, Finland.

出版信息

Spine J. 2014 Oct 1;14(10):2392-6. doi: 10.1016/j.spinee.2014.01.047. Epub 2014 Jan 30.

Abstract

BACKGROUND CONTEXT

In lumbar spinal stenosis (LSS), conservative treatment is usually the first choice of treatment. If conservative treatment fails, surgery is indicated. Psychological factors such as depression and anxiety are known to affect the outcome of surgery. Previous studies on depression and surgery outcome using long follow-up times are scarce.

PURPOSE

The purpose of this study was to investigate the effect of depressive symptoms on the surgical outcome during a 5-year follow-up among patients with LSS.

STUDY DESIGN

A prospective observational study.

PATIENT SAMPLE

Patient sample included 102 LSS patients who needed surgical treatment.

OUTCOME MEASURES

The outcome of surgery was evaluated with the Oswestry Disability Index (ODI), visual analog scale pain assessment, and self-reported walking capacity.

METHODS

The patients completed a set of questionnaires preoperatively and 3 and 6 months, as well as 1, 2, and 5 years after the surgery. Depressive symptoms were assessed with the Beck Depression Inventory. The depressive burden was estimated by summing all individual Beck Depression Inventory scores. Statistical analyses included cross-sectional group comparisons and linear regression analyses. No conflicts of interest.

RESULTS

On 5-year follow-up, a high depressive burden associated with a poorer outcome of surgery when assessed with the ODI. In linear regression analysis, a high depressive burden associated with higher ODI score.

CONCLUSIONS

Even slightly elevated long-term depressive symptoms in LSS patients are associated with an increased risk of a poorer functional ability after decompressive surgery.

摘要

背景

在腰椎管狭窄症(LSS)中,保守治疗通常是首选治疗方法。若保守治疗失败,则需进行手术。已知抑郁和焦虑等心理因素会影响手术结果。以往关于抑郁与手术结果的长期随访研究较少。

目的

本研究旨在调查腰椎管狭窄症患者在5年随访期间抑郁症状对手术结果的影响。

研究设计

一项前瞻性观察研究。

患者样本

患者样本包括102例需要手术治疗的腰椎管狭窄症患者。

结局指标

采用奥斯威斯利功能障碍指数(ODI)、视觉模拟评分法疼痛评估和自我报告的步行能力来评估手术结果。

方法

患者在术前、术后3个月、6个月以及术后1年、2年和5年完成一系列问卷调查。采用贝克抑郁量表评估抑郁症状。通过将所有个体的贝克抑郁量表得分相加来估计抑郁负担。统计分析包括横断面组间比较和线性回归分析。无利益冲突。

结果

在5年随访中,当用ODI评估时,高抑郁负担与较差的手术结果相关。在线性回归分析中,高抑郁负担与较高的ODI评分相关。

结论

即使腰椎管狭窄症患者长期抑郁症状略有升高,也与减压手术后功能能力较差的风险增加有关。

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