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在成人喉气管狭窄的治疗中寻求微创手术与喉气管切除术之间的平衡。

Finding balance between minimally invasive surgery and laryngotracheal resection in the management of adult laryngotracheal stenosis.

作者信息

Halmos György B, Schuiringa Fréderique S A M, Pálinkó Dóra, van der Laan Tom P, Dikkers Frederik G

机构信息

Department of Otolaryngology, Head and Neck Surgery, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands,

出版信息

Eur Arch Otorhinolaryngol. 2014 Jul;271(7):1967-71. doi: 10.1007/s00405-014-2901-1. Epub 2014 Feb 2.

Abstract

Management of adult laryngotracheal stenosis is complex and several treatment options are known. The present study focuses on finding the right balance between minimally invasive surgery and laryngotracheal resection by reviewing a single institution's experiences. Retrospective analysis was performed of all adult and adolescent patients with laryngotracheal stenosis who underwent treatment in a tertiary referral center, between 1990 and 2012. Age, gender, etiology, treatment, recurrence, pre- and post-operative peak flow (PF), and pre- and post-treatment subjective complain scores (SCS) were registered. 87 patients with 267 interventions were analyzed. There were 238 dilatation tracheoscopies, 22 open surgeries and various other endoscopic procedures registered. Idiopathic stenoses required the most dilatation tracheoscopies, while post-tracheotomy stenoses required the least. Patients in the post-intubation and post-tracheotomy groups were significantly more often treated with open surgery compared to those in the granulomatosis with polyangiitis (GPA) and idiopathic groups. The gain in PF flow after dilatation tracheoscopy was significantly higher in the idiopathic group compared to the other groups. The median SCS of dyspnoea decreased in the whole population, while other SCS did not change remarkably. Repeated endoscopic procedures are recommended in patients with severe systemic disease which do not allow open surgery or when other comorbidities contraindicate open surgery. Open surgery very often offers the definitive solution in the treatment of laryngotracheal stenosis and cannot be avoided when the laryngeal or the tracheal framework is damaged. Patients' personal preferences have to be considered in the pre-operative assessment process.

摘要

成人喉气管狭窄的治疗较为复杂,已知有多种治疗选择。本研究通过回顾单一机构的经验,致力于在微创手术和喉气管切除术之间找到恰当的平衡。对1990年至2012年间在一家三级转诊中心接受治疗的所有成人和青少年喉气管狭窄患者进行了回顾性分析。记录了年龄、性别、病因、治疗方法、复发情况、术前和术后的峰值流速(PF)以及治疗前后的主观症状评分(SCS)。对87例患者的267次干预治疗进行了分析。共记录了238次扩张气管镜检查、22次开放手术以及各种其他内镜手术。特发性狭窄需要进行的扩张气管镜检查次数最多,而气管切开术后狭窄需要的次数最少。与肉芽肿性多血管炎(GPA)组和特发性组相比,插管后和气管切开术后组的患者接受开放手术的频率明显更高。与其他组相比,特发性组在扩张气管镜检查后PF流速的增加显著更高。整个人群中呼吸困难的中位SCS有所下降,而其他SCS没有明显变化。对于患有严重全身性疾病而无法进行开放手术或存在其他合并症而禁忌开放手术的患者,建议重复进行内镜手术。开放手术通常能为喉气管狭窄的治疗提供最终解决方案,当喉或气管支架受损时则无法避免。在术前评估过程中必须考虑患者的个人偏好。

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