Monnier Philippe, George Mercy, Monod Marie-Laure, Lang Florian
Department of Otolaryngology and Head and Neck Surgery, Hôpital Cantonal Universitaire Vaudois, 1011 Lausanne, Switzerland.
Eur Arch Otorhinolaryngol. 2005 Aug;262(8):602-8. doi: 10.1007/s00405-005-0948-8. Epub 2005 Jul 15.
Over the last decade, improvement of CO2 lasers with the microspot and ultrapulse technologies has broadened the indications for endoscopic CO2-laser resection of benign laryngotracheal stenosis (LTS). This article reviews 100 patients treated solely by endoscopic means for a LTS. There were 47 grade III, 41 grade II and 12 grade I stenoses according to the Myer-Cotton classification. The postoperative results show that the improvement to a nearly normal (>80% luminal size) airway declines from 92% (11/12 patients) for grade I to 46% (19/41 patients) for grade II and 13% (6/47 patients) for grade III stenoses. When compared to open surgery for more severe grades of stenosis (31 grade IV, 66 grade III and 3 grade II stenoses), the results of the endoscopy group is much less favorable: 36% of patients in the endoscopy group versus 76% of patients in the open surgery group were rehabilitated to a normal respiration without exertional dyspnea and 38% versus 5% patients remained tracheotomy dependent. However, if strict selection and therapeutic criteria are respected, a significant number of grade I and II stenoses, and to a lesser degree of grade III stenoses, can be improved to a nearly normal airway by endoscopic means only. The endoscopic treatment is potentially less invasive and risky and only needs a short hospital stay. To try this as a first treatment modality in a selected group of patients is worthwhile, provided that this endoscopic treatment is not repeated a second time, if the stenosis recurs to its initial grade after a primary CO2-laser treatment. Some guidelines for safe endoscopic treatment modalities with of the CO2 laser, dilatation and/or stenting are proposed.
在过去十年中,采用微光斑和超脉冲技术的二氧化碳激光得到改进,这拓宽了内镜下二氧化碳激光切除良性喉气管狭窄(LTS)的适应证。本文回顾了仅通过内镜治疗的100例LTS患者。根据迈尔 - 科顿分类,有47例III级、41例II级和12例I级狭窄。术后结果显示,气道改善至接近正常(管腔大小>80%)的比例从I级的92%(11/12例患者)降至II级的46%(19/41例患者)和III级狭窄的13%(6/47例患者)。与更严重狭窄程度(31例IV级、66例III级和3例II级狭窄)的开放手术相比,内镜组的结果要差得多:内镜组36%的患者与开放手术组76%的患者恢复到无运动性呼吸困难的正常呼吸,且内镜组38%的患者与开放手术组5%的患者仍依赖气管切开。然而,如果遵循严格的选择和治疗标准,相当数量的I级和II级狭窄,以及程度较轻的III级狭窄,仅通过内镜手段就可改善至接近正常的气道。内镜治疗潜在的侵入性和风险较小,且仅需短期住院。在一组选定的患者中尝试将其作为首选治疗方式是值得的,前提是如果在初次二氧化碳激光治疗后狭窄恢复到初始级别,这种内镜治疗不再重复进行。本文还提出了一些关于二氧化碳激光、扩张和/或支架置入等安全内镜治疗方式的指南。