'Bobo-Newton 综合征'：人类最好朋友带来的意外“礼物”。
'Bobo-Newton syndrome': An unwanted gift from man's best friend.
机构信息
Department of Internal Medicine; McGill University - Jewish General Hospital;
Division of Infectious Diseases, Division of Allergy & Clinical Immunology, Department of Medicine, Department of Medical Microbiology, Department of Human Genetics, McGill University Health Centre, Montreal, Quebec.
出版信息
Can J Infect Dis Med Microbiol. 2013 Winter;24(4):209-14. doi: 10.1155/2013/930158.
Capnocytophaga canimorsus is a facultative Gram-negative bacillus that is typically a constituent of the oral flora of dogs and cats. It was first isolated by Bobo and Newton in 1976 from a man presenting with meningitis following a dog bite. Transmission to humans follows various animal-related injuries, which may be gross or subtle. C canimorsus can cause a spectrum of syndromes ranging from skin and soft tissue infection to invasive disease such as meningitis or endocarditis. The present article reports a case of C canimorsus meningitis in a patient with the classic risk factor of alcoholic liver cirrhosis. Clinical suspicion was confirmed by culture and genetic identification of the blood isolate. The present article reviews the Capnocytophaga genus, the clinical syndromes most commonly associated with this zoonotic organism, its laboratory identification and treatment.
贪噬二氧化碳噬纤维菌是一种兼性革兰氏阴性杆菌，通常是狗和猫口腔菌群的一部分。1976 年，Bobo 和 Newton 首次从一名被狗咬伤后出现脑膜炎的男子身上分离出该菌。人类感染是通过各种与动物有关的损伤传播的，这些损伤可能是明显的，也可能是细微的。贪噬二氧化碳噬纤维菌可引起从皮肤和软组织感染到侵袭性疾病如脑膜炎或心内膜炎等一系列综合征。本文报告了一例经典危险因素为酒精性肝硬化的贪噬二氧化碳噬纤维菌脑膜炎患者。临床怀疑通过血液分离株的培养和遗传鉴定得到证实。本文综述了贪噬二氧化碳噬纤维菌属、与这种人畜共患病原体最常相关的临床综合征、其实验室鉴定和治疗。
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