Bang D, Honma T, Saito T, Nakagawa S, Ueki H, Lee S
Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea.
Acta Derm Venereol. 1988;68(1):33-40.
We observed small dermal blood vessels embolized by thrombus at the sites of needle-prick reaction as well as erythema nodosum-like lesions in 4 patients with Behçet's disease, by means of electron microscopy. The ultrastructural finding associated with overproductive proliferation of the endothelial cells leading to obliteration of the vascular lumen was the sporadical appearance of degenerated cells among proliferating endothelial cells in both cutaneous manifestations. These degenerated cells showed contraction changes and may be involved in thrombogenesis.
通过电子显微镜观察，我们在4例白塞病患者的针刺反应部位发现有小真皮血管被血栓栓塞，以及出现了结节性红斑样病变。在这两种皮肤表现中，与内皮细胞过度增殖导致血管腔闭塞相关的超微结构发现是，在增殖的内皮细胞中散在出现退化细胞。这些退化细胞呈现收缩变化，可能参与血栓形成。
