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扁平苔藓中的HLA - DR和DQ抗原

HLA-DR and DQ antigens in lichen planus.

作者信息

Valsecchi R, Bontempelli M, Rossi A, Bellavita P, Barcella A, Di Landro A, Cainelli T

机构信息

Department of Dermatology, Ospedali Riuniti di Bergamo, Italy.

出版信息

Acta Derm Venereol. 1988;68(1):77-80.

PMID:2449017
Abstract

A study on HLA-DR and DQ typing in 40 patients with lichen planus (26 males and 14 females) and in 92 normal blood donors of both sexes was performed. Twenty-seven patients had cutaneous lesions, 11 cutaneous and mucosal involvement and 2 patients had oral erosive lesions. Serological typing revealed a highly significant increase of HLA-DR 1 antigen in the patient group. No difference has been observed on the prevalence of DR1 antigen among the different clinical status of the disease.

摘要

对40例扁平苔藓患者(26例男性和14例女性)以及92例男女正常献血者进行了HLA - DR和DQ分型研究。27例患者有皮肤损害,11例有皮肤和黏膜受累,2例有口腔糜烂性损害。血清学分型显示患者组中HLA - DR1抗原显著增加。在该疾病的不同临床状态中,未观察到DR1抗原患病率的差异。

相似文献

1
HLA-DR and DQ antigens in lichen planus.扁平苔藓中的HLA - DR和DQ抗原
Acta Derm Venereol. 1988;68(1):77-80.
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Clinical, Epidemiological, and Dermoscopic Features of Different Clinical Variants of Cutaneous Lichen Planus in the Indian Population: A Prospective Observational Study.印度人群中不同临床类型皮肤扁平苔藓的临床、流行病学及皮肤镜特征:一项前瞻性观察研究
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The Immunogenetics of Lichen Planus.扁平苔藓的免疫遗传学。
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Cutaneous and mucosal lichen planus: a comprehensive review of clinical subtypes, risk factors, diagnosis, and prognosis.
皮肤和黏膜扁平苔藓:临床亚型、危险因素、诊断及预后的全面综述
ScientificWorldJournal. 2014 Jan 30;2014:742826. doi: 10.1155/2014/742826. eCollection 2014.
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Oesophageal lichen planus: a missed diagnosis.食管扁平苔藓:漏诊病例
J R Soc Med. 2006 Jun;99(6):318-20. doi: 10.1177/014107680609900621.
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Lichen planus and liver diseases: a multicentre case-control study. Gruppo Italiano Studi Epidemiologici in Dermatologia (GISED).扁平苔藓与肝脏疾病:一项多中心病例对照研究。意大利皮肤病流行病学研究组(GISED)。
BMJ. 1990 Jan 27;300(6719):227-30. doi: 10.1136/bmj.300.6719.227.