对缺血再灌注大鼠心脏进行的31-P核磁共振光谱分析：伊洛前列素的作用
31-P-NMR-spectroscopy on ischemic and reperfused rat hearts: effects of iloprost.
作者信息
Pissarek M, Gründer W, Keller T
机构信息
Department of Cardiovascular Surgery, Karl-Marx-University, Leipzig, GDR.
出版信息
Biomed Biochim Acta. 1987;46(8-9):S564-7.
PMID:2449192
Abstract
Effects of iloprost on the behaviour of high energy phosphate contents were investigated in global ischemic and reperfused rat hearts prepared according to Langendorff. Iloprost application before and after 20 min of ischemia at a dosage of 9-12 pg/g heart weight x min improved the availability of high energy phosphates as was shown by CP/Pi ratio during the first hour of reperfusion.
摘要
在按照Langendorff法制备的全脑缺血再灌注大鼠心脏中，研究了伊洛前列素对高能磷酸含量变化的影响。在缺血20分钟之前及之后，以9 - 12皮克/克心脏重量×分钟的剂量应用伊洛前列素，结果显示，在再灌注的第一个小时内，磷酸肌酸/无机磷酸（CP/Pi）比值表明高能磷酸的可利用性得到了改善。
Zotero 插件