玛颇马兜铃中的倍半萜吲哚生物碱
Terpenoid indole alkaloids from Mappianthus iodoides Hand.-Mazz.
机构信息
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Zhangjiang Hi-Tech Park, Shanghai 201203, PR China.
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Zhangjiang Hi-Tech Park, Shanghai 201203, PR China.
出版信息
Phytochemistry. 2014 Apr;100:76-85. doi: 10.1016/j.phytochem.2014.01.004. Epub 2014 Feb 1.
Ten terpenoid indole alkaloids, mappiodines A-C and mappiodosides A-G, together with eight known compounds, were isolated from stems of Mappianthus iodoides Hand.-Mazz. Their structures were elucidated by spectroscopic analyses including 1D, 2D NMR, MS and CD methods. The ten compounds were evaluated for their cytotoxic activity, but were inactive.
从八角枫科八角枫属植物华瓜木 Mappianthus iodoides Hand.-Mazz. 的茎中分离得到 10 个新的倍半萜吲哚生物碱 mappiodines A-C 和 mappiodosides A-G，以及 8 个已知化合物。通过 1D、2D NMR、MS 和 CD 等光谱分析方法鉴定了它们的结构。对这 10 个化合物进行了细胞毒活性评价，但均无活性。
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