Tkachenko Olga, Olson Elizabeth A, Weber Mareen, Preer Lily A, Gogel Hannah, Killgore William D S
Center for Depression, Anxiety, and Stress Research, McLean Hospital, 115 Mill Street, Belmont, MA, 02478, USA.
Exp Brain Res. 2014 May;232(5):1567-74. doi: 10.1007/s00221-014-3827-y. Epub 2014 Feb 5.
Sleep problems often co-occur with psychopathological conditions and affective dysregulation. Individuals with mood disorders have significantly higher rates of sleep disturbances than healthy individuals, and among those with mood disorders, sleep problems are associated with lower rates of remission and response to treatment. Sleep disruption may itself be a risk factor for various forms of psychopathology, as experimental sleep deprivation has been found to lead to increased affective, cognitive, and somatic symptoms within healthy volunteers. However, little is known about the relationship between recurring sleep complaints in a naturalistic environment and symptoms of psychopathology among healthy individuals. In the present study, 49 healthy adults (21 males and 28 females) reported sleep quality and completed the Personality Assessment Inventory, a standardized self-report assessment of symptoms of psychopathology. Consistent with prior published findings during total sleep deprivation, individuals endorsing self-reported naturally occurring sleep problems showed higher scores on scales measuring somatic complaints, anxiety, and depression. Furthermore, the reported frequency of sleep disturbance was closely linked with the severity of self-reported symptoms. While causal directionality cannot be inferred, these findings support the notion that sleep and emotional functioning are closely linked.
睡眠问题常常与精神病理状况及情感失调同时出现。患有情绪障碍的个体出现睡眠障碍的几率显著高于健康个体,而且在患有情绪障碍的人群中,睡眠问题与较低的缓解率及治疗反应率相关。睡眠中断本身可能是各种精神病理形式的一个风险因素,因为实验性睡眠剥夺已被发现会导致健康志愿者出现更多的情感、认知及躯体症状。然而,对于自然环境中反复出现的睡眠问题与健康个体的精神病理症状之间的关系,人们了解甚少。在本研究中,49名健康成年人(21名男性和28名女性)报告了睡眠质量并完成了《人格评估量表》,这是一项对精神病理症状进行标准化自我报告的评估。与先前关于完全睡眠剥夺的已发表研究结果一致,认可自我报告的自然发生的睡眠问题的个体在测量躯体不适、焦虑和抑郁的量表上得分更高。此外,报告的睡眠障碍频率与自我报告症状的严重程度密切相关。虽然无法推断因果方向性,但这些发现支持了睡眠与情绪功能密切相关这一观点。