Libedinsky Camilo, Smith David V, Teng Chieh Schen, Namburi Praneeth, Chen Vanessa W, Huettel Scott A, Chee Michael W L
Neuroscience and Behavioral Disorders Program, Duke-NUS Graduate Medical School Singapore, Singapore.
Front Behav Neurosci. 2011 Oct 24;5:70. doi: 10.3389/fnbeh.2011.00070. eCollection 2011.
Even a single night of total sleep deprivation (SD) can have dramatic effects on economic decision making. Here we tested the novel hypothesis that SD influences economic decisions by altering the valuation process. Using functional magnetic resonance imaging we identified value signals related to the anticipation and the experience of monetary and social rewards (attractive female faces). We then derived decision value signals that were predictive of each participant's willingness to exchange money for brief views of attractive faces in an independent market task. Strikingly, SD altered decision value signals in ventromedial prefrontal cortex (VMPFC) in proportion to the corresponding change in economic preferences. These changes in preference were independent of the effects of SD on attention and vigilance. Our results provide novel evidence that signals in VMPFC track the current state of the individual, and thus reflect not static but constructed preferences.
即使仅仅一个晚上完全剥夺睡眠（SD），也会对经济决策产生显著影响。在此，我们检验了一个新的假设，即睡眠剥夺通过改变估值过程来影响经济决策。我们使用功能磁共振成像识别了与预期以及货币和社会奖励（有吸引力的女性面孔）体验相关的价值信号。然后，我们得出了决策价值信号，这些信号可预测每个参与者在独立市场任务中用金钱换取短暂观看有吸引力面孔的意愿。令人惊讶的是，睡眠剥夺按比例改变了腹内侧前额叶皮层（VMPFC）中的决策价值信号，这与经济偏好的相应变化一致。这些偏好变化独立于睡眠剥夺对注意力和警觉性的影响。我们的结果提供了新的证据，表明腹内侧前额叶皮层中的信号追踪个体的当前状态，因此反映的不是固定不变而是构建出来的偏好。
