Department of Ultrasound, the Affiliated Hospital of North Sichuan Medical College, Nanchong City, Sichuan Province 637000, China.
Department of Radiology, the Affiliated Hospital of North Sichuan Medical College, Nanchong City, Sichuan Province 637000, China.
Korean J Radiol. 2014 Jan-Feb;15(1):80-6. doi: 10.3348/kjr.2014.15.1.80. Epub 2014 Jan 8.
The aim of our study was to evaluate the differences between sclerotherapy with and without ethanol concentration monitoring for the treatment of simple renal cysts.
Sixty-seven patients with 70 simple renal cysts were randomly assigned to two groups in a 12-month prospective controlled trial. One group (group A) was treated with computed tomography (CT)-guided sclerotherapy without ethanol concentration monitoring (33 patients with 35 cysts), whereas the other group (group B) had ethanol concentration monitoring (34 patients with 35 cysts) during the procedure. Treatment outcomes between the two groups were compared 12 months later with follow-up ultrasound examination.
After the 12-month follow-up period, the overall success rate was 74.3% in group A and 94.3% in group B (p = 0.022). The mean cyst size before and after treatment was 8.6 ± 2.0 cm and 2.3 ± 2.9 cm, respectively, in group A, and 8.4 ± 1.7 cm and 0.8 ± 1.9 cm, respectively, in group B. The final size of the cysts in group B was significantly smaller than that in group A (p = 0.015). The likelihood of treatment with ethanol concentration monitoring being successful was approximately 16 times higher than without ethanol concentration monitoring (p = 0.026; odds ratio = 15.7; 95% confidence interval: 1.38-179.49). There were no major complications in either group.
Monitoring of Hounsfield units (HU) of ethanol by CT is an effective method in the treatment of simple renal cysts with ethanol sclerotherapy. The ethanol sclerotherapy procedure can be terminated at the point of clear fluid aspiration because the HU (-190) of CT scan corresponds to it.
本研究旨在评估单纯性肾囊肿治疗中是否进行乙醇浓度监测的硬化治疗之间的差异。
67 例 70 个单纯性肾囊肿患者在 12 个月前瞻性对照试验中随机分为两组。一组(A 组)接受 CT 引导下的硬化治疗,不进行乙醇浓度监测(33 例,35 个囊肿),另一组(B 组)在手术过程中进行乙醇浓度监测(34 例,35 个囊肿)。12 个月后通过超声随访比较两组的治疗效果。
12 个月随访后,A 组总成功率为 74.3%,B 组为 94.3%(p = 0.022)。A 组治疗前后囊肿平均大小分别为 8.6 ± 2.0 cm 和 2.3 ± 2.9 cm,B 组分别为 8.4 ± 1.7 cm 和 0.8 ± 1.9 cm。B 组囊肿的最终大小明显小于 A 组(p = 0.015)。有乙醇浓度监测的治疗成功率约为无乙醇浓度监测的 16 倍(p = 0.026;优势比= 15.7;95%置信区间:1.38-179.49)。两组均无严重并发症。
CT 监测乙醇的 Hounsfield 单位(HU)是乙醇硬化治疗单纯性肾囊肿的有效方法。当抽吸到清亮液体时,即可终止乙醇硬化治疗,因为 CT 扫描的 HU(-190)与之对应。