Ivanov V M, Nadeev F I, Chelyshev Iu A
Nauchnye Doki Vyss Shkoly Biol Nauki. 1987(12):52-5.
Substance P (10 and 100 ng/ml) stimulates the proliferation of basal cells from rat's tongue epithelium in primary cultures with 2.5% fetal calf serum. In serum-free medium substance P have no effect on the epithelial cell growth. This neuropeptide secreted by afferent nerve fibers of the tongue epithelium is suggested to have a neurotrophic influence on epithelial cells controlling their proliferation.
P物质（10和100纳克/毫升）可刺激原代培养的、含有2.5%胎牛血清的大鼠舌上皮基底细胞的增殖。在无血清培养基中，P物质对上皮细胞生长没有影响。舌上皮传入神经纤维分泌的这种神经肽被认为对控制上皮细胞增殖具有神经营养作用。
