Yoshimura Junko, Asano Yoshihide, Takahashi Takehiro, Uwajima Yuta, Kagami Shinji, Honda Hiromi, Idezuki Takeo, Igarashi Atsuyuki, Sato Shinichi
a Department of Dermatology , University of Tokyo Graduate School of Medicine , Tokyo , Japan.
b Department of Dermatology , Kanto Medical Center NTT EC , Tokyo , Japan.
Mod Rheumatol. 2016;26(2):302-6. doi: 10.3109/14397595.2013.875640. Epub 2014 Feb 5.
Scleredema adultorum, also known as scleredema of Buschke, is a rare connective tissue disease with unknown etiology, which is characterized by diffuse skin induration of face, neck, upper chest, back, shoulders and arms. Although there is no established treatment for this disease, the efficacy of phototherapy has been reported. We herein describe a case of scleredema adultorum successfully treated with narrow-band ultraviolet B and discuss a potential mechanism explaining its efficacy for fibrotic skin diseases.
成人硬肿病,也称为布希克硬肿病,是一种病因不明的罕见结缔组织疾病,其特征为面部、颈部、上胸部、背部、肩部和手臂出现弥漫性皮肤硬结。尽管尚无针对该疾病的确立治疗方法,但已有光疗疗效的报道。我们在此描述一例成功接受窄谱中波紫外线治疗的成人硬肿病病例,并讨论其对纤维化皮肤病疗效的潜在机制。