Dusemund Frank, Baty Florent, Brutsche Martin H
Division of Pneumology, Department of Internal Medicine, Kantonsspital St. Gallen, St. Gallen, Switzerland.
Tob Control. 2015 Jul;24(4):404-7. doi: 10.1136/tobaccocontrol-2013-051290. Epub 2014 Feb 5.
Only a few studies have examined the effect of public smoking bans on respiratory conditions. These showed reduced admission rates for different respiratory diseases.
The objective of the present study was to evaluate the effect of the public smoking ban implemented in Graubünden, Switzerland, on the incidence of acute hospital admissions for acute exacerbated chronic obstructive pulmonary disease (AECOPD).
We searched a database, including all nationwide hospitalisations in Switzerland, for AECOPD and analysed incidence rates before and after introduction of the smoking ban using Poisson regression and incidence rate ratios (IRRs).
After introduction of the smoking ban, we observed a significant 22.4% decrease in the incidence of AECOPD hospitalisations in Graubünden (IRR=0.78 (0.68 to 0.88), p<0.001). In the same period, the incidence of AECOPD hospitalisations only slightly decreased by 7.0% in the rest of Switzerland (IRR=0.93 (0.91 to 0.95), p<0.001). The observed reduction in AECOPD hospitalisation incidence was significantly greater in GR than in the rest of CH (p=0.008).
Our study supports the limited body of evidence demonstrating that a reduction of secondhand smoke by legislated bans on smoking is associated with reduced rates of admission to hospital for respiratory conditions, hereby shown for AECOPD, in addition to the meanwhile well-documented impact on cardiovascular disease.
仅有少数研究探讨了公共场所禁烟对呼吸道疾病的影响。这些研究表明不同呼吸道疾病的住院率有所降低。
本研究的目的是评估瑞士格劳宾登州实施的公共场所禁烟对急性加重慢性阻塞性肺疾病(AECOPD)急性住院发生率的影响。
我们在一个包含瑞士所有全国性住院病例的数据库中搜索AECOPD,并使用泊松回归和发病率比(IRR)分析禁烟实施前后的发病率。
实施禁烟后,我们观察到格劳宾登州AECOPD住院发生率显著下降了22.4%(IRR = 0.78(0.68至0.88),p < 0.001)。同期,瑞士其他地区AECOPD住院发生率仅略有下降,为7.0%(IRR = 0.93(0.91至0.95),p < 0.001)。格劳宾登州(GR)观察到的AECOPD住院发生率下降幅度明显大于瑞士其他地区(CH)(p = 0.008)。
我们的研究支持了有限的证据表明,通过立法禁烟减少二手烟与呼吸道疾病住院率降低有关,在此以AECOPD为例证明了这一点,同时也有充分记录显示其对心血管疾病有影响。