Kadam Dinesh
Department of Plastic and Reconstructive Surgery, A J Institute of Medical Sciences and A J Hospital and Research Centre, Kuntikana, Mangalore, Karnataka, India.
Indian J Plast Surg. 2013 May;46(2):265-74. doi: 10.4103/0970-0358.118603.
The threat of lower limb loss is seen commonly in severe crush injury, cancer ablation, diabetes, peripheral vascular disease and neuropathy. The primary goal of limb salvage is to restore and maintain stability and ambulation. Reconstructive strategies differ in each condition such as: Meticulous debridement and early coverage in trauma, replacing lost functional units in cancer ablation, improving vascularity in ischaemic leg and providing stable walking surface for trophic ulcer. The decision to salvage the critically injured limb is multifactorial and should be individualised along with laid down definitive indications. Early cover remains the standard of care, delayed wound coverage not necessarily affect the final outcome. Limb salvage is more cost-effective than amputations in a long run. Limb salvage is the choice of procedure over amputation in 95% of limb sarcoma without affecting the survival. Compound flaps with different tissue components, skeletal reconstruction; tendon transfer/reconstruction helps to restore function. Adjuvant radiation alters tissue characters and calls for modification in reconstructive plan. Neuropathic ulcers are wide and deep often complicated by osteomyelitis. Free flap reconstruction aids in faster healing and provides superior surface for offloading. Diabetic wounds are primarily due to neuropathy and leads to six-fold increase in ulcerations. Control of infections, aggressive debridement and vascular cover are the mainstay of management. Endovascular procedures are gaining importance and have reduced extent of surgery and increased amputation free survival period. Though the standard approach remains utilising best option in the reconstruction ladder, the recent trend shows running down the ladder of reconstruction with newer reliable local flaps and negative wound pressure therapy.
下肢丧失的风险常见于严重挤压伤、癌症切除、糖尿病、周围血管疾病和神经病变。保肢的主要目标是恢复并维持稳定性和行走能力。在每种情况下,重建策略各不相同,例如:创伤时进行细致清创和早期覆盖,癌症切除时替换缺失的功能单位,改善缺血腿部的血运,以及为营养性溃疡提供稳定的行走表面。挽救严重受伤肢体的决定是多因素的,应根据既定的明确指征进行个体化决策。早期覆盖仍然是标准治疗方法,延迟伤口覆盖不一定会影响最终结果。从长远来看,保肢比截肢更具成本效益。在95%的肢体肉瘤病例中,保肢是优于截肢的手术选择,且不影响生存率。带有不同组织成分的复合皮瓣、骨骼重建;肌腱转移/重建有助于恢复功能。辅助放疗会改变组织特性,因此需要调整重建计划。神经性溃疡通常又宽又深,常并发骨髓炎。游离皮瓣重建有助于更快愈合,并为减轻压力提供优质表面。糖尿病伤口主要由神经病变引起,会使溃疡发生率增加六倍。控制感染、积极清创和血管覆盖是主要治疗手段。血管内手术正变得越来越重要,减少了手术范围,延长了无截肢生存期。尽管标准方法仍然是在重建阶梯中采用最佳选择,但最近的趋势是使用更新的可靠局部皮瓣和负压伤口治疗,从重建阶梯上往下走。