Beltramone Marion, Donnet Anne
Department of Neurology, Clinical Neuroscience Federation, La Timone Hospital, Marseille, France.
Department of Evaluation and Treatment of Pain, Clinical Neuroscience Federation, La Timone Hospital, France INSERM U929, CHU de Clermont-Ferrand, France
Cephalalgia. 2014 Jul;34(8):633-7. doi: 10.1177/0333102414520763. Epub 2014 Feb 6.
Status migrainosus (SM) and migraine aura status (MAS) are two migraine complications. Few data exist in literature.
This 11-year retrospective study in one French center describes patients' characteristics, modifications of the migraine before complication, evolution after the episode and management in patients who had SM or MAS according to International Classification of Headache Disorders, second edition (ICHD-II) criteria.
Among 8821 patients, 24 had SM, three had MAS and one had both forms. Mean duration of SM was 4.8 weeks and four weeks for MAS. Stress and menstruation were the main precipitating factors for SM (68.8% and 31.3%, respectively). No precipitating factor was found for MAS. For a majority of patients, the frequency of migraine attack was the same before and after SM or MAS. SM and MAS occurred more frequently in patients with initial low-frequency migraine attacks. Eight patients had a relapse of SM and three of MAS. Fifteen were hospitalized for amitriptyline intravenous treatment.
SM and MAS are rare. Our results highlight a high rate of relapse and a similar frequency of migraine attacks before and after SM.
偏头痛持续状态（SM）和偏头痛先兆持续状态（MAS）是两种偏头痛并发症。文献中相关数据较少。
在法国一个中心进行的这项为期11年的回顾性研究，根据国际头痛疾病分类第二版（ICHD-II）标准，描述了患有SM或MAS患者的特征、并发症发生前偏头痛的变化、发作后的演变情况及治疗。
在8821例患者中，24例患有SM，3例患有MAS，1例同时患有两种类型。SM的平均持续时间为4.8周，MAS为4周。压力和月经是SM的主要诱发因素（分别为68.8%和31.3%）。未发现MAS的诱发因素。对于大多数患者而言，SM或MAS前后偏头痛发作频率相同。SM和MAS在初始发作频率较低的偏头痛患者中更为常见。8例患者出现SM复发，3例出现MAS复发。15例患者因静脉注射阿米替林而住院治疗。
SM和MAS较为罕见。我们的研究结果表明复发率较高，且SM前后偏头痛发作频率相似。
