Vakili S M, Sharbatdaran Majid, Noorbaran Askari, Siadati Sepideh, Moslemi D, Shafahi Shahriar
Medical oncologist, assistant professor of Babol University of medical sciences, Babol, Iran.
Pathologist, assistant professor of Babol University of medical sciences, Babol, Iran.
Int J Hematol Oncol Stem Cell Res. 2014;8(1):46-50.
Colorectal cancer most commonly metastasizes to the liver and lung. Metastatic colon carcinoma (MCC) to the breast is extremely rare. Krukenberg tumor is an uncommon metastatic tumor of the ovary.
A 38 years woman presented with abdominal pain. In evaluation colon cancer was diagnosed at stage 3. FOLFOX chemotherapy was done. After one year she developed Krukenberg tumor. Few days after ovarian tumor resection breast tumor was diagnosed. In immunohistochemistry both ovarian and breast tumors was CK7 negative, CK20 positive, compatible with colon cancer origin. This is the first case of simultaneous metastasis of colon cancer to two rare sites.
结直肠癌最常转移至肝脏和肺。结肠癌转移至乳腺极为罕见。库肯勃瘤是一种罕见的卵巢转移性肿瘤。
一名38岁女性因腹痛就诊。评估后诊断为3期结肠癌,接受了FOLFOX化疗。一年后她出现了库肯勃瘤。卵巢肿瘤切除术后数天,诊断出乳腺肿瘤。免疫组化显示,卵巢和乳腺肿瘤均为CK7阴性、CK20阳性,符合结肠癌来源。这是首例结肠癌同时转移至两个罕见部位的病例。