Tarsitano Achille, Foschini Maria Pia, Farneti Paolo, Pasquini Ernesto, Marchetti Claudio
Maxillofacial Surgery Unit, Alma Mater Studiorum University of Bologna, Bologna, Italy.
Department of Hematology and Oncology, Section of Pathological Anatomy, Bellaria Hospital, University of Bologna, Bologna, Italy.
J Craniomaxillofac Surg. 2014 Dec;42(8):1562-5. doi: 10.1016/j.jcms.2014.01.014. Epub 2014 Jan 14.
Pleomorphic salivary adenomas are the most common benign neoplasms affecting the salivary glands. Very occasionally however, metastatic lesions are identified in patients with a history of PSA, which, on detailed pathological evaluation, are found to exhibit all the histological hallmarks of the preceding benign lesions. Diagnosis of benign metastasizing pleomorphic adenoma of the salivary gland is extremely rare and still under debate. We present the first case-report in literature of multiple metachronous nasal cavity, scalp and encephalic metastases of a pleomorphic adenoma of the parotid gland in a young girl.
多形性腺瘤是影响唾液腺的最常见良性肿瘤。然而,非常罕见的是,在有多形性腺瘤病史的患者中发现转移性病变,经详细病理评估,这些病变表现出先前良性病变的所有组织学特征。唾液腺良性转移性多形性腺瘤的诊断极为罕见,目前仍存在争议。我们报告了文献中首例关于一名年轻女孩腮腺多形性腺瘤发生鼻腔、头皮和脑多发异时性转移的病例报告。