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影像学与预后因素之间的相关性:乳腺癌的分子分类

Correlation between imaging and prognostic factors: molecular classification of breast cancers.

作者信息

Boisserie-Lacroix M, Bullier B, Hurtevent-Labrot G, Ferron S, Lippa N, Mac Grogan G

机构信息

Unité de sénologie département d'imagerie médicale, institut Bergonié, 229, cours de l'Argonne, 33076 Bordeaux cedex, France.

Unité de sénologie département d'imagerie médicale, institut Bergonié, 229, cours de l'Argonne, 33076 Bordeaux cedex, France.

出版信息

Diagn Interv Imaging. 2014 Feb;95(2):227-33. doi: 10.1016/j.diii.2013.12.013. Epub 2014 Feb 6.

DOI:10.1016/j.diii.2013.12.013
PMID:24508482
Abstract

The new molecular classification of breast cancers defines cancer sub-groups with a distinct prognosis and response to treatment. Studies on the literature deal with the imaging of each tumour sub-type. The radiologist should be familiar with them in order to adapt the care of an aggressive sub-type. In view of the current knowledge, the following have been significantly more often observed: mammographical spiculated mass with echogenic halo in luminal A sub-type; architectural distortion in luminal B sub-type; an irregular mass with indistinct margin comprising microcalcifications, with an abrupt interface in the sonography, or non-sonographic mass in the HER2 sub-type; a very hypoechogenic, lobulated mass with indistinct or microlobulated margin, with an abrupt interface, sometimes pseudo-benign, in the triple-negative sub-type.

摘要

乳腺癌的新分子分类定义了具有不同预后和治疗反应的癌症亚组。文献研究涉及每种肿瘤亚型的影像学表现。放射科医生应熟悉这些表现,以便对侵袭性亚型进行适当的治疗。基于目前的知识,以下情况更为常见:管腔A型亚型中伴有回声晕的乳腺钼靶毛刺状肿块;管腔B型亚型中的结构扭曲;HER2亚型中边界不清、包含微钙化的不规则肿块,超声检查时有突然的界面,或非超声肿块;三阴性亚型中极低回声、分叶状肿块,边界不清或呈微叶状,有突然的界面,有时呈假良性。

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