Scimeca Manuel, Bischetti Simone, Lamsira Harpreet Kaur, Bonfiglio Rita, Bonanno Elena
University of Rome "Tor Vergata", Department of Biomedicine and Prevention.
Eur J Histochem. 2018 Mar 15;62(1):2841. doi: 10.4081/ejh.2018.2841.
The Energy Dispersive X-ray (EDX) microanalysis is a technique of elemental analysis associated to electron microscopy based on the generation of characteristic Xrays that reveals the presence of elements present in the specimens. The EDX microanalysis is used in different biomedical fields by many researchers and clinicians. Nevertheless, most of the scientific community is not fully aware of its possible applications. The spectrum of EDX microanalysis contains both semi-qualitative and semi-quantitative information. EDX technique is made useful in the study of drugs, such as in the study of drugs delivery in which the EDX is an important tool to detect nanoparticles (generally, used to improve the therapeutic performance of some chemotherapeutic agents). EDX is also used in the study of environmental pollution and in the characterization of mineral bioaccumulated in the tissues. In conclusion, the EDX can be considered as a useful tool in all works that require element determination, endogenous or exogenous, in the tissue, cell or any other sample.
能量色散X射线（EDX）微分析是一种与电子显微镜相关的元素分析技术，它基于特征X射线的产生，揭示了标本中存在的元素。许多研究人员和临床医生在不同的生物医学领域使用EDX微分析。然而，大多数科学界人士并未充分意识到其可能的应用。EDX微分析的光谱包含半定性和半定量信息。EDX技术在药物研究中很有用，例如在药物递送研究中，EDX是检测纳米颗粒的重要工具（一般用于提高某些化疗药物的治疗性能）。EDX还用于环境污染研究以及组织中生物累积矿物质的表征。总之，在所有需要确定组织、细胞或任何其他样品中内源性或外源性元素的工作中，EDX都可被视为一种有用的工具。
