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光学相干断层扫描在葡萄膜炎诊断与治疗中的应用

Optical coherence tomography in the diagnosis and management of uveitis.

作者信息

Pakzad-Vaezi Kaivon, Or Chris, Yeh Steven, Forooghian Farzin

机构信息

Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, B.C.

Department of Ophthalmology, Emory Eye Center, Emory University School of Medicine, Atlanta, Ga.

出版信息

Can J Ophthalmol. 2014 Feb;49(1):18-29. doi: 10.1016/j.jcjo.2013.10.005. Epub 2013 Dec 22.

DOI:10.1016/j.jcjo.2013.10.005
PMID:24513352
Abstract

Optical coherence tomography (OCT) has become an integral tool in the imaging of numerous diseases of the posterior segment. The diagnostic investigation of infectious and noninfectious uveitic conditions often requires multiple imaging modalities in the appropriate clinical context. Modern OCT technology has proved useful not only in the diagnostic investigation of these conditions, but also in monitoring of their clinical course and therapeutic response. Inflammation-induced changes at the level of the retina, retinal pigment epithelium, and choroid can now easily be identified in these conditions using OCT. Prognostic information on visual acuity outcome can also be estimated based on OCT findings. Numerous OCT findings have been described in the setting of the various uveitides. Although none of these findings appear to be pathognomonic for diagnosis of specific uveitic syndromes, in the appropriate clinical context they can add a great deal of information in the diagnosis and management of uveitis.

摘要

光学相干断层扫描(OCT)已成为后段众多疾病成像的重要工具。在适当的临床背景下,对感染性和非感染性葡萄膜炎疾病的诊断研究通常需要多种成像方式。现代OCT技术不仅在这些疾病的诊断研究中被证明是有用的,而且在监测其临床病程和治疗反应方面也很有用。现在,在这些疾病中使用OCT可以很容易地识别出视网膜、视网膜色素上皮和脉络膜水平的炎症引起的变化。基于OCT检查结果还可以估计视力预后信息。在各种葡萄膜炎的情况下,已经描述了许多OCT检查结果。虽然这些发现似乎都不是特定葡萄膜炎综合征诊断的特征性表现,但在适当的临床背景下,它们可以为葡萄膜炎的诊断和管理提供大量信息。

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