Glickman Urological and Kidney Institute, Cleveland Clinic, 9500 Euclid Ave Q10-1, Cleveland, OH, 44195, USA,
Curr Urol Rep. 2014 Apr;15(4):400. doi: 10.1007/s11934-014-0400-y.
Urinary urgency after synthetic sling surgery may be persistent urgency that preceded the surgery or de novo urgency that developed after surgery. Recent studies estimate a 40 % rate of persistent urgency after synthetic sling surgery in women with mixed urinary incontinence. Causes of de novo urgency after synthetic sling surgery include postoperative urinary tract infection (7.4-17.4 %), bladder outlet obstruction (1.9-19.7 %), perforation of the urinary tract (0.5-5 %), and idiopathic urgency (0-28 %). Given the temporal relationship of de novo urgency developing after surgery, until proven otherwise, one should assume that the etiology is obstruction. Evaluation includes a history and physical exam, urinalysis, and post-void residual. Cystoscopy and urodynamics may help rule out surgical complications. Management is based on the etiology of the urgency. Urinary tract perforation and bladder outlet obstruction are treated with surgical intervention. Idiopathic de novo or persistent urgency after synthetic sling surgery are treated similarly to idiopathic overactive bladder, with behavioral therapy as first-line treatment, antimuscarinics or beta-agonists as second-line therapy, and intravesical onabotulinumtoxinA or sacral neuromodulation as third-line therapy.
尿失禁术后急迫性尿失禁可能是手术前已存在的持续性急迫性尿失禁,也可能是手术后新发的急迫性尿失禁。最近的研究估计,混合性尿失禁女性在接受合成吊带手术后持续性急迫性尿失禁的发生率为 40%。合成吊带手术后新发急迫性尿失禁的原因包括术后尿路感染(7.4%-17.4%)、膀胱出口梗阻(1.9%-19.7%)、尿路穿孔(0.5%-5%)和特发性急迫性尿失禁(0%-28%)。鉴于新发急迫性尿失禁发生在手术后的时间关系,在没有其他证据之前,应假设病因是梗阻。评估包括病史和体格检查、尿液分析和残余尿量。膀胱镜检查和尿动力学检查有助于排除手术并发症。治疗基于急迫性尿失禁的病因。尿路穿孔和膀胱出口梗阻采用手术干预治疗。对于合成吊带手术后新发的特发性或持续性急迫性尿失禁,与特发性逼尿肌过度活动症的治疗方法类似,一线治疗为行为治疗,二线治疗为抗胆碱能药物或β-受体激动剂,三线治疗为膀胱内注射肉毒毒素 A 或骶神经调节。