Department of Urology, The First Affiliated Hospital of Kunming Medical University, Kunming 650032, China.
School of Mechanical and Electric Engineering, Kunming University of Science and Technology, Kunming 650093, China.
Medicina (Kaunas). 2022 Oct 22;58(11):1506. doi: 10.3390/medicina58111506.
Background and Objectives: pseudo urgency syndrome among patients with mixed incontinence (MUI) causes and the corresponding treatment strategies is explored. Materials and Methods: A total of 40 patients with MUI are treated with transobturator tape (TOT) and/or solifenacin succinate. Further, 30 patients with simple stress urinary incontinence (SUI) that were treated with transobturator tape (TOT) from the period of December 2018 to August 2020 are retrospectively analyzed; then, their clinical characteristics and therapeutic effects were summarized and analyzed. Results: The effective rates of SUI symptoms in MUI and simple SUI groups were 85% and 90%, respectively; further, the difference was noted as not statistically significant (P > 0.05). Among the 40 patients with MUI, 12 patients had unstable bladder contraction, and the other 28 patients showed normal bladder compliance. The treatment effectiveness rates of SUI symptoms in patients with unstable bladder contraction and normal bladder compliance were 83.3% and 85.7%, respectively; further, no significant difference was noted (P > 0.05). However, the effective rates of urge urinary incontinence (UUI) were 50% and 85.7%, respectively, however the difference was noted as statistically significant (P < 0.05). Conclusions: Most of the UUI symptoms in MUI patients may be “pseudo urgency syndrome” caused by the worry about the leakage of urine, rather than a real sense of UUI that is caused by excessive bladder excitement. Direct surgical treatment in patients with MUI can improve the symptoms of urinary incontinence, and the effect is more obvious in patients with urinary frequency who have normal bladder compliance according to urodynamics.
探讨混合性尿失禁（MUI）患者假性急迫综合征的病因及相应的治疗策略。
对 40 例 MUI 患者行经闭孔吊带（TOT）及/或琥珀酸索利那新治疗，回顾性分析 2018 年 12 月至 2020 年 8 月期间单纯压力性尿失禁（SUI）行 TOT 手术的 30 例患者的临床特征及疗效，总结并分析其治疗策略。
MUI 组与单纯 SUI 组 SUI 症状有效率分别为 85%和 90%，差异无统计学意义（P＞0.05）；MUI 组中 12 例逼尿肌不稳定，28 例膀胱顺应性正常，逼尿肌不稳定与膀胱顺应性正常患者 SUI 症状有效率分别为 83.3%和 85.7%，差异无统计学意义（P＞0.05）；但急迫性尿失禁（UUI）症状有效率分别为 50%和 85.7%，差异有统计学意义（P＜0.05）。
MUI 患者 UUI 症状多为因担心漏尿而产生的“假性急迫综合征”，而非真正意义上的逼尿肌过度兴奋引起的 UUI。MUI 患者直接行手术治疗可改善患者的尿失禁症状，且对以尿频为主、尿动力学检查提示膀胱顺应性正常的患者效果更为明显。
