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多发性溶骨性病变。

Multiple osteolytic lesions.

作者信息

Vinayachandran Divya, Sankarapandian Sathasivasubramanian

机构信息

Department of Oral Medicine and Radiology, Sri Ramaswamy Memorial Kattankulathur Dental College and Hospitals, Chennai, Tamil Nadu, India.

Faculty of Dental Sciences, Sri Ramachandra University, Chennai, Tamil Nadu, India.

出版信息

J Clin Imaging Sci. 2013 Aug 31;3(Suppl 1):6. doi: 10.4103/2156-7514.117460. eCollection 2013.

DOI:10.4103/2156-7514.117460
PMID:24516769
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3906660/
Abstract

Several systemic diseases initially present with various oral manifestations. Investigation of these oral symptoms may at times lead to the diagnosis of grave underlying life-threatening conditions. We present one such case, where the patient manifested with gross enlargement of the mandible, along with lesions in the lower limbs. These lesions were the initial manifestation and on further investigations the patient was diagnosed with multiple myeloma.

摘要

几种全身性疾病最初会表现出各种口腔症状。对这些口腔症状的检查有时可能会导致诊断出严重的潜在危及生命的疾病。我们在此呈现这样一个病例，该患者表现为下颌骨明显肿大，同时下肢有病变。这些病变是最初的表现，进一步检查后患者被诊断为多发性骨髓瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd74/3906660/285a3d6accff/JCIS-3-6-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd74/3906660/3dc6555c72e2/JCIS-3-6-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd74/3906660/be6f4d1e5ccf/JCIS-3-6-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd74/3906660/a6202eaee4b8/JCIS-3-6-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd74/3906660/04ac6f9b83e1/JCIS-3-6-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd74/3906660/a064e9430aba/JCIS-3-6-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd74/3906660/b77843a7a554/JCIS-3-6-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd74/3906660/285a3d6accff/JCIS-3-6-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd74/3906660/3dc6555c72e2/JCIS-3-6-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd74/3906660/be6f4d1e5ccf/JCIS-3-6-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd74/3906660/a6202eaee4b8/JCIS-3-6-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd74/3906660/04ac6f9b83e1/JCIS-3-6-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd74/3906660/a064e9430aba/JCIS-3-6-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd74/3906660/b77843a7a554/JCIS-3-6-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd74/3906660/285a3d6accff/JCIS-3-6-g009.jpg

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本文引用的文献

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J Maxillofac Oral Surg. 2010 Jun;9(2):209-12. doi: 10.1007/s12663-010-0050-7. Epub 2010 Sep 22.
2
Multiple myeloma: 2012 update on diagnosis, risk-stratification, and management.多发性骨髓瘤：2012 年诊断、风险分层和治疗的更新。
Am J Hematol. 2012 Jan;87(1):78-88. doi: 10.1002/ajh.22237.
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Abnormal radiological features in a multiple myeloma patient: a case report and radiological review of myelomas.多发性骨髓瘤患者的异常影像学特征：病例报告及骨髓瘤影像学复习
牙医能否通过口腔表现来检测多发性骨髓瘤？
Hematol Transfus Cell Ther. 2018 Jan-Mar;40(1):43-49. doi: 10.1016/j.bjhh.2017.08.006. Epub 2017 Nov 24.
Dentomaxillofac Radiol. 2011 Dec;40(8):513-8. doi: 10.1259/dmfr/74265829.
4
Guidelines for the diagnosis and management of multiple myeloma 2011.2011年多发性骨髓瘤诊断与管理指南
Br J Haematol. 2011 Jul;154(1):32-75. doi: 10.1111/j.1365-2141.2011.08573.x. Epub 2011 May 14.
5
Beyond the CRAB symptoms: a study of presenting clinical manifestations of multiple myeloma.除了 CRAB 症状以外：一项多发性骨髓瘤临床表现的研究。
Clin Lymphoma Myeloma Leuk. 2010 Dec;10(6):464-8. doi: 10.3816/CLML.2010.n.080.
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Multiple myeloma: diagnosis and treatment.多发性骨髓瘤：诊断与治疗
Am Fam Physician. 2008 Oct 1;78(7):853-9.
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Early-onset multiple myeloma: an illustrative case report.早发性多发性骨髓瘤：一例病例报告
J Manipulative Physiol Ther. 2007 Sep;30(7):543-9. doi: 10.1016/j.jmpt.2007.07.002.
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Medical management update: multiple myeloma.医学管理更新：多发性骨髓瘤
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 May;103(5):599-609. doi: 10.1016/j.tripleo.2006.10.026. Epub 2007 Feb 7.