医学管理更新：多发性骨髓瘤

Medical management update: multiple myeloma.

作者信息

Stoopler Eric T, Vogl Dan T, Stadtmauer Edward A

机构信息

Department of Oral Medicine, University of Pennsylvania School of Dental Medicine, Philadelphia, PA 19104, USA.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 May;103(5):599-609. doi: 10.1016/j.tripleo.2006.10.026. Epub 2007 Feb 7.

DOI:10.1016/j.tripleo.2006.10.026

PMID:17291793

Abstract

Multiple myeloma (MM) is a hematologic malignancy characterized by abnormal proliferation of immunoglobulin-secreting plasma cells. Manifestations of MM may include anemia, osteolytic lesions, and renal dysfunction. Treatment for this disease chiefly consists of corticosteroids, bisphosphonates, chemotherapy, and hematopoietic stem-cell transplantation. This medical management update will review recent clinical and therapeutic advances in the field of MM and highlight issues that are important to the oral health care provider.

摘要

多发性骨髓瘤（MM）是一种血液系统恶性肿瘤，其特征为分泌免疫球蛋白的浆细胞异常增殖。MM的表现可能包括贫血、溶骨性病变和肾功能不全。该疾病的治疗主要包括使用皮质类固醇、双膦酸盐、化疗和造血干细胞移植。本医学管理更新将回顾MM领域最近的临床和治疗进展，并强调对口腔医疗保健提供者来说重要的问题。