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伊朗呼罗珊省北部儿童和青少年维生素D缺乏症的患病率及其相关因素

Prevalence of vitamin D deficiency and its related factors in children and adolescents living in North Khorasan, Iran.

作者信息

Habibesadat Shakeri, Ali Khakshour, Shabnam Jalili Moghaddam, Arash Akaberi

出版信息

J Pediatr Endocrinol Metab. 2014 May;27(5-6):431-6. doi: 10.1515/jpem-2013-0198.

Abstract

INTRODUCTION

Vitamin D deficiency is recognized as an epidemic among children. The present study has analyzed serum 25 hydroxyvitamin D [25(OH)D] levels of children living in the city of Bojnurd, located in the North Khorasan province of Iran.

METHODS

In this cross-sectional study, 361 subjects (175 boys and 186 girls) aged 7-18 years participated; 25(OH)D, parathyroid hormone (PTH), and anthropometric measurements were obtained. Deficiency, insufficiency and sufficiency of vitamin D was assessed based on the relationship between 25(OH)D and PTH. Vitamin D status was reported according to gender and age group of participants.

RESULTS

The prevalence of vitamin D deficiency was 16.1% and its insufficiency was 25.2%. Girls had higher levels of vitamin D deficiency (30.6%) and insufficiency (38.7%). The mean level of serum 25(OH)D decreased in older age groups. The age-adjusted odds of serum 25(OH)D <30 was 21.12 higher in girls compared to boys.

CONCLUSION

The prevalence of vitamin D deficiency and insufficiency was high. The ratio in girls was higher than in boys.

摘要

引言

维生素D缺乏在儿童中已成为一种普遍现象。本研究分析了居住在伊朗呼罗珊省北部博季努尔市儿童的血清25羟维生素D [25(OH)D]水平。

方法

在这项横断面研究中,361名年龄在7至18岁的受试者(175名男孩和186名女孩)参与其中;测量了他们的25(OH)D、甲状旁腺激素(PTH)以及人体测量数据。根据25(OH)D与PTH之间的关系评估维生素D的缺乏、不足和充足情况。根据参与者的性别和年龄组报告维生素D状态。

结果

维生素D缺乏的患病率为16.1%,不足率为25.2%。女孩的维生素D缺乏(30.6%)和不足(38.7%)水平更高。血清25(OH)D的平均水平在年龄较大的组中有所下降。与男孩相比,女孩血清25(OH)D<30的年龄调整后比值高21.12倍。

结论

维生素D缺乏和不足的患病率很高。女孩中的比例高于男孩。

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