Faculty of Medicine, University of Brasilia, Brasilia, Federal District, Brazil; Getulio Vargas University Hospital, Federal University of Amazonas, Manaus, Amazonas, Brazil.
Pharmacoepidemiol Drug Saf. 2014 May;23(5):507-14. doi: 10.1002/pds.3583. Epub 2014 Feb 12.
To assess the prevalence of medicine use in adults of Brasilia and to elucidate the associated factors.
A cross-sectional study was conducted with adults (18 to 65 years) living in Brasilia, who were selected using a two-stage probabilistic sampling and interviewed in their home, from February to May 2012. The primary outcome was the use of medicines in the last 7 days. A Poisson regression with robust variance was employed to adjust for covariates following a hierarchical model.
The study included 1820 individuals (11% losses), 60% of which were women, and the mean age was 37 ± 12.6 years. The prevalence of drug consumption was 35.7% (95% confidence interval [95%CI]: 33.5%-37.9%). Medicine consumption was significantly higher in women (prevalence ratio [PR] = 1.54; 95%CI: 1.28-1.85); unemployed or retired people (PR = 1.35; 95%CI: 1.15-1.59); people with hypertension (PR = 2.33; 95%CI: 2.00-2.71), diabetes (PR = 1.46; 95%CI: 1.22-1.74), depression (PR = 1.32; 95%CI: 1.13-1.53), or other chronic diseases (PR = 1.50; 95%CI: 1.26-1.79); and study participants who had a recent medical consultation (PR = 1.49; 95%CI: 1.29-1.71). Medication use was significantly higher at older ages. The participants obtained about half of the drugs from the Brazilian public health system, but this access was significantly different according to the economic class.
Medication use was common among adults living in Brasilia and is associated with sex, age, health conditions, and access to healthcare.
评估巴西利亚成年人的用药情况，并阐明相关因素。
这是一项横断面研究，对象为居住在巴西利亚的成年人（18 至 65 岁），采用两阶段概率抽样方法选取，并于 2012 年 2 月至 5 月在其家中进行访谈。主要结局是过去 7 天内的用药情况。采用具有稳健方差的 Poisson 回归，根据分层模型对协变量进行调整。
本研究共纳入 1820 名个体（11%的失访率），其中 60%为女性，平均年龄为 37±12.6 岁。药物使用率为 35.7%（95%置信区间[95%CI]：33.5%-37.9%）。女性（患病率比[PR] = 1.54；95%CI：1.28-1.85）、失业或退休人员（PR = 1.35；95%CI：1.15-1.59）、高血压（PR = 2.33；95%CI：2.00-2.71）、糖尿病（PR = 1.46；95%CI：1.22-1.74）、抑郁症（PR = 1.32；95%CI：1.13-1.53）或其他慢性疾病患者（PR = 1.50；95%CI：1.26-1.79）用药率显著更高；近期有医疗咨询的参与者（PR = 1.49；95%CI：1.29-1.71）用药率也显著更高。随着年龄的增长，用药率显著增加。参与者约有一半的药物来自巴西公共卫生系统，但这种获取途径根据经济阶层存在显著差异。
巴西利亚成年人的用药情况较为普遍，与性别、年龄、健康状况和获得医疗保健的机会有关。
