Gustafson C J, O'Neill J, Hix E, McLaren D T, Buxton O M, Feldman S R
Center for Dermatology Research, Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Skin Res Technol. 2014 Nov;20(4):510-4. doi: 10.1111/srt.12147. Epub 2014 Feb 13.
BACKGROUND/PURPOSE: Actigraphy monitors are used to monitor sleep and scratching. Previous studies have implemented these monitors to evaluate behavior in adult patients with atopic dermatitis. However, such monitoring devices have been implemented in a paucity of studies involving pediatric patients with atopic dermatitis. The purpose of this study was to assess the feasibility of actigraphy monitoring in children with mild-to-severe atopic dermatitis.
A total of six pediatric subjects were recruited. The severity of atopic dermatitis at the wrist area was assessed prior to placement of the wristband monitor. After wearing the wristbands for 7 days, subjects returned to clinic to undergo reassessment of the wrist area to determine if atopic dermatitis was exacerbated by the wrist-worn device. Data on sleep quality and how often patients wore the wristband monitors were also collected. No subjective data from the subjects or parents/caregivers were collected on tolerability of the monitors.
None of the subjects exhibited exacerbation of atopic dermatitis at the wrist area after wearing the actigraphy monitors for 7 days. No adverse events were reported. Pediatric patients with atopic dermatitis exhibited less total sleep time compared with children evaluated in previous actigraphy studies.
Actigraphy wristband monitoring can be used to continuously assess disease severity in children with atopic dermatitis.
背景/目的：活动记录仪用于监测睡眠和搔抓情况。既往研究已使用这些记录仪来评估成年特应性皮炎患者的行为。然而，此类监测设备在涉及儿童特应性皮炎患者的研究中应用较少。本研究的目的是评估活动记录仪监测在轻至重度特应性皮炎患儿中的可行性。
共招募了6名儿科受试者。在佩戴腕带式监测仪之前，先评估腕部区域特应性皮炎的严重程度。佩戴腕带7天后，受试者返回诊所，再次评估腕部区域，以确定佩戴腕部设备是否会使特应性皮炎加重。同时还收集了睡眠质量数据以及患者佩戴腕带式监测仪的频率。未收集受试者或父母/照料者关于监测仪耐受性的主观数据。
在佩戴活动记录仪7天后，所有受试者腕部区域的特应性皮炎均未加重。未报告不良事件。与既往活动记录仪研究中评估的儿童相比，患有特应性皮炎的儿科患者总睡眠时间较短。
活动记录仪腕带监测可用于持续评估特应性皮炎患儿的疾病严重程度。
