Hwang Ji Hye, Lee Chang-Hyung, Lee Hae Hyun, Kim Soo Yeon
1 Department of Physical Medicine and Rehabilitation, Samsung Medical Center, Center for Clinical Research, Sungkyunkwan University School of Medicine , Seoul, Republic of Korea.
Lymphat Res Biol. 2014 Jun;12(2):89-94. doi: 10.1089/lrb.2013.0030. Epub 2014 Feb 12.
Abstract Various techniques are available for measuring the status of lymphedema. A modified imaging technique using ultrasonography was developed to measure the structure of soft tissue area in a cost-effective manner. The purpose of this study was to measure the reliability and the accuracy of this new method. Ultrasonography was performed on both arms of twenty healthy female participants. At 10 cm above (AE) and below (BE) the elbow crease, soft tissue thickness at medial, lateral, inferior, and superior locations were measured by two examiners with minimal unnecessary pressure. After measuring twice on 16 sites for each participant, the amount of soft tissue in the cross-sectional area (ΔCSA) was acquired by a designed formulation. The ΔCSA was also compared with volumetry data (Perometer(®)). Cronbach's alpha coefficient test was used for statistics. The intra-class and inter-class reliability measurements for all soft tissue areas were very strong (α=0.980 and 0.960, respectively; p<0.01). All AE and BE reliabilities showed very strong correlation and strong correlation of inter-BE measurement. All reliabilities of ΔCSA were very strong (≥0.950). All CCs (correlation coefficients) between ΔCSA, circumference, and volumetry were strong for AE and BE measurements, except for ΔCSA and circumference at BE. The strongest CC was between volumetry and circumference measurements. This study suggests that measuring the ΔCSA by ultrasonography could be an alternative way to measure the status of soft tissue indirectly with structural consideration.
摘要 有多种技术可用于测量淋巴水肿的状况。我们开发了一种改良的超声成像技术，以经济有效的方式测量软组织区域的结构。本研究的目的是测量这种新方法的可靠性和准确性。对20名健康女性参与者的双臂进行超声检查。在肘横纹上方10厘米（AE）和下方（BE）处，由两名检查者在施加最小不必要压力的情况下测量内侧、外侧、下方和上方位置的软组织厚度。在对每位参与者的16个部位进行两次测量后，通过设计的公式获取横截面积中的软组织量（ΔCSA）。还将ΔCSA与体积测量数据（Perometer(®)）进行了比较。采用克朗巴赫α系数检验进行统计学分析。所有软组织区域的组内和组间可靠性测量都非常强（分别为α = 0.980和0.960；p < 0.01）。所有AE和BE的可靠性显示出非常强的相关性以及BE测量之间的强相关性。ΔCSA的所有可靠性都非常强（≥0.950）。对于AE和BE测量，除了BE处的ΔCSA和周长外，ΔCSA、周长和体积测量之间的所有相关系数（CC）都很强。最强的CC是体积测量和周长测量之间的。本研究表明，通过超声测量ΔCSA可能是一种在考虑结构因素的情况下间接测量软组织状况的替代方法。
