Simmering Jacob E, Polgreen Linnea A, Cavanaugh Joseph E, Polgreen Philip M
Department of Pharmacy Practice and Science, University of Iowa, Iowa City, Iowa.
Infect Control Hosp Epidemiol. 2014 Mar;35(3):251-6. doi: 10.1086/675281.
To determine whether well-child visits are a risk factor for subsequent influenza-like illness (ILI) visits within a child's family.
Retrospective cohort.
Using data from the Medical Expenditure Panel Survey from the years 1996-2008, we identified 84,595 families. For each family, we determined those weeks in which a well-child visit or an ILI visit occurred. We identified 23,776 well-child-visit weeks and 97,250 ILI-visit weeks. We fitted a logistic regression model, where the binary dependent variable indicated an ILI clinic visit in a particular week. Independent variables included binary indicators to denote a well-child visit in the concurrent week or one of the previous 2 weeks, the occurrence of the ILI visit during the influenza season, and the presence of children in the family in each of the age groups 0-3, 4-7, and 8-17 years. Socioeconomic variables were also included. We also estimated the overall cost of well-child-exam-related ILI using data from 2008.
We found that an ILI office visit by a family member was positively associated with a well-child visit in the same or one of the previous 2 weeks (odds ratio, 1.54). This additional risk translates to potentially 778,974 excess cases of ILI per year in the United States, with a cost of $500 million annually.
Our results should encourage ambulatory clinics to strictly enforce infection control recommendations. In addition, clinics could consider time-shifting of well-child visits so as not to coincide with the peak of the influenza season.
确定儿童健康检查是否是儿童家庭中随后出现流感样疾病(ILI)就诊的危险因素。
回顾性队列研究。
利用1996 - 2008年医疗支出面板调查的数据,我们识别出84,595个家庭。对于每个家庭,我们确定了发生儿童健康检查或ILI就诊的那些周。我们识别出23,776个儿童健康检查就诊周和97,250个ILI就诊周。我们拟合了一个逻辑回归模型,其中二元因变量表示特定周的ILI门诊就诊。自变量包括二元指标,用于表示同一周或前两周之一的儿童健康检查就诊、流感季节期间ILI就诊的发生情况,以及家庭中0 - 3岁、4 - 7岁和8 - 17岁各年龄组儿童的存在情况。还纳入了社会经济变量。我们还利用2008年的数据估计了与儿童健康检查相关的ILI的总体费用。
我们发现家庭成员的ILI门诊就诊与同一周或前两周之一的儿童健康检查就诊呈正相关(优势比,1.54)。这种额外的风险在美国每年可能导致额外778,974例ILI病例,每年花费5亿美元。
我们的结果应促使门诊诊所严格执行感染控制建议。此外,诊所可考虑错开儿童健康检查时间,使其不与流感季节高峰重合。