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论亨廷顿舞蹈症语言异常的神经语言学本质

On the neurolinguistic nature of language abnormalities in Huntington's disease.

作者信息

Wallesch C W, Fehrenbach R A

机构信息

Department of Neurology, University of Freiburg, Federal Republic of Germany.

出版信息

J Neurol Neurosurg Psychiatry. 1988 Mar;51(3):367-73. doi: 10.1136/jnnp.51.3.367.

DOI:10.1136/jnnp.51.3.367
PMID:2452241
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1032862/
Abstract

Spontaneous language of 18 patients suffering from Huntington's disease and 15 dysarthric controls suffering from Friedreich's ataxia were investigated. In addition, language functions in various modalities were assessed with the Aachen Aphasia Test (AAT). The Huntington patients exhibited deficits in the syntactical complexity of spontaneous speech and in the Token Test, confrontation naming, and language comprehension subtests of the AAT, which are interpreted as resulting from their dementia. Errors affecting word access mechanisms and production of syntactical structures as such were not encountered.

摘要

对18名患有亨廷顿舞蹈症的患者以及15名患有弗里德赖希共济失调且存在构音障碍的对照者的自发语言进行了研究。此外,运用亚琛失语症测试(AAT)对各种语言模式下的语言功能进行了评估。亨廷顿舞蹈症患者在自发言语的句法复杂性、AAT的符号测试、对答命名及语言理解子测试中均表现出缺陷,这些缺陷被解释为是由其痴呆症所致。未发现影响词汇提取机制及句法结构生成的错误。

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Hand muscle reflexes following electrical stimulation in choreatic movement disorders.舞蹈病运动障碍中电刺激后的手部肌肉反射
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本文引用的文献

1
Dysarthric symptomatology of Friedreich's ataxia.弗里德赖希共济失调的构音障碍症状学
Brain Lang. 1980 May;10(1):39-50. doi: 10.1016/0093-934x(80)90036-x.
2
The mysterious motor function of the basal ganglia: the Robert Wartenberg Lecture.基底神经节的神秘运动功能:罗伯特·瓦尔滕贝格讲座
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Basal ganglia participation in language pathology.基底神经节在语言病理学中的参与情况。
Brain Lang. 1982 Jul;16(2):281-99. doi: 10.1016/0093-934x(82)90087-6.
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Word production and comprehension in Alzheimer's disease: the breakdown of semantic knowledge.阿尔茨海默病中的词汇生成与理解:语义知识的瓦解
Brain Lang. 1983 May;19(1):124-41. doi: 10.1016/0093-934x(83)90059-7.
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Neuropsychologic findings in Friedreich's ataxia.
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Neuropsychological deficits in early, middle, and late stage Huntington's disease as measured by the Luria-Nebraska Neuropsychological Battery.
Int J Neurosci. 1981;14(1-2):95-100. doi: 10.3109/00207458108985820.
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Dementia in Huntington disease: a cross-sectional analysis of intellectual decline.亨廷顿病中的痴呆:智力衰退的横断面分析
Adv Neurol. 1983;38:229-38.
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Confrontation naming impairment in dementia.痴呆中的对指命名障碍。
Brain Lang. 1983 May;19(1):98-114. doi: 10.1016/0093-934x(83)90057-3.
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[Subcortical aphasia. Neruolinguistic and x-ray computed tomography studies of 25 cases].[皮质下失语症。25例的神经语言学与X线计算机断层扫描研究]
Rev Neurol (Paris). 1984;140(12):695-710.
10
A study of naming errors in dysphasic and in demented patients.一项关于失语症患者和痴呆患者命名错误的研究。
Neuropsychologia. 1971 Dec;9(4):437-43. doi: 10.1016/0028-3932(71)90008-x.