Lian Jing Jing, Ma Li Li, Hu Jian Wei, Chen Shi Yao, Qin Wen Zheng, Xu Mei Dong, Zhou Ping Hong, Yao Li Qing
Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
J Dig Dis. 2014 May;15(5):224-9. doi: 10.1111/1751-2980.12136.
The aim of this study was to evaluate the safety and efficacy of endoscopic balloon dilatation (EBD) for benign esophageal strictures after ESD for early esophageal neoplasms.
Data of 335 patients who were treated with ESD for early esophageal neoplasms from October 2006 to August 2012 were retrospectively reviewed. The characteristics of the patients who underwent EBD for post-ESD stricture were analyzed.
A total of 117 dilatation procedures were performed in 29 patients with post-ESD esophageal stricture. The mean number of EBD sessions was 4.0 (range 1-15) and no complications occurred during the procedures. The median follow-up period for the 29 patients since their last session of EBD was 20 months (range 1-48 months). Of the 28 patients who were followed up for more than 3 months after achieving dysphagia relief, two had recurrent dysphasia and EBD was reintroduced. The treatment success rate was 92.9% (26/28).
EBD is a safe and effective modality for the treatment of benign esophageal stricture after ESD for early esophageal neoplasms.
本研究旨在评估内镜下球囊扩张术（EBD）治疗早期食管肿瘤内镜黏膜下剥离术（ESD）后良性食管狭窄的安全性和有效性。
回顾性分析2006年10月至2012年8月期间335例行ESD治疗早期食管肿瘤患者的数据。分析接受EBD治疗ESD术后狭窄患者的特征。
29例ESD术后食管狭窄患者共进行了117次扩张手术。EBD治疗次数平均为4.0次（范围1 - 15次），手术过程中未发生并发症。29例患者自最后一次EBD治疗后的中位随访期为20个月（范围1 - 48个月）。在吞咽困难缓解后随访超过3个月的28例患者中，2例出现复发性吞咽困难并再次接受EBD治疗。治疗成功率为92.9%（26/28）。
EBD是治疗早期食管肿瘤ESD术后良性食管狭窄的一种安全有效的方法。
