Zhang Yue, Zhang Baozhen, Wang Yidan, Zhang Jingjing, Wu Yufan, Xiao Tingyue, Liao Ye, Bao Yiwen, Qiu Hongyu, Sun Siyu, Guo Jintao
Department of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China.
J Transl Int Med. 2020 Sep 25;8(3):135-145. doi: 10.2478/jtim-2020-0022. eCollection 2020 Sep.
Endoscopic submucosal dissection (ESD) has become the main treatment for early esophageal cancer. While treating the disease, ESD may also cause postoperative esophageal stricture, which is a global issue that needs resolution. Various methods have been applied to resolve the problem, such as mechanical dilatation, glucocorticoids, anti-scarring drugs, and regenerative medicine; however, no standard treatment regimen exists. This article describes and evaluates the strengths and limitations of new and promising potential strategies for the treatment and prevention of esophageal strictures.
内镜下黏膜剥离术（ESD）已成为早期食管癌的主要治疗方法。在治疗该疾病时，ESD也可能导致术后食管狭窄，这是一个需要解决的全球性问题。人们已应用多种方法来解决这一问题，如机械扩张、糖皮质激素、抗瘢痕药物和再生医学；然而，目前尚无标准的治疗方案。本文描述并评估了治疗和预防食管狭窄的新的、有前景的潜在策略的优势和局限性。
