Jurik A G, Helmig O, Graudal H
Department of Diagnostic Radiology, Municipal Hospital, Denmark.
Scand J Rheumatol Suppl. 1988;70:3-15. doi: 10.3109/03009748809093406.
A follow-up study of 13 patients with pustulosis palmoplantaris (PPP) and skeletal disease is reported. A prolonged and fluctuating course occurred in all patients. Nine patients had anterior chest wall involvement with erosions or ankylosis of the sternoclavicular, first sternocostal and/or manubriosternal joint together with sclerosis and often hyperostosis of adjacent bones, ossification/calcification of the first costal cartilage, and in 7 patients of the costoclavicular ligament. Spinal involvement in the form of spondylodiscitis, sclerosis of vertebral bodies, syndesmophytes, paravertebral ossifications and/or spondyloarthritis occurred in 11 patients, three of whom also had involvement of the sacroiliac joints. One patient had sclerosis of a pubic and ischial bone. Peripheral arthritis or tenosynovitis occurred in 5 patients, two of whom had signs of enthesopathy, and one also erosions. The presence of a distinct PPP syndrome is suggested.
本文报道了一项对13例掌跖脓疱病（PPP）合并骨骼疾病患者的随访研究。所有患者病程均呈迁延且波动状态。9例患者前胸壁受累，表现为胸锁关节、第一胸肋关节和/或胸骨柄体关节糜烂或强直，伴相邻骨骼硬化及常出现的骨质增生、第一肋软骨骨化/钙化，7例患者肋锁韧带受累。11例患者出现脊柱受累，表现为脊椎间盘炎、椎体硬化、骨桥形成、椎旁骨化和/或脊柱关节炎，其中3例患者还累及骶髂关节。1例患者耻骨和坐骨硬化。5例患者出现外周关节炎或腱鞘炎，其中2例有附着点病体征，1例还有糜烂。提示存在一种独特的PPP综合征。
