Jurik A G, Ternowitz T
Department of Diagnostic Radiology, Municipal Hospital, Aarhus, Denmark.
J Am Acad Dermatol. 1988 Apr;18(4 Pt 1):666-71. doi: 10.1016/s0190-9622(88)70088-2.
Fourteen randomly selected patients with pustulosis palmoplantaris were examined to determine the frequency of skeletal involvement. Symptoms and both clinical and radiographic signs of skeletal disease occurred in five patients (36%). Four patients had erosive and/or sclerotic changes in the region of the sternoclavicular, the first sternocostal, and/or the manubriosternal joint, in two with additional ossification of the costoclavicular ligament. Two patients had spinal involvement, one paravertebral ossifications, and the other sequelae of anterior spondylodiskitis. Peripheral joint complaints without radiographically detectable erosions, but with periarticular new bone formation, occurred in three patients. The skeletal changes are probably not incidental and seems to constitute a seronegative spondyloarthropathy associated with pustulosis palmoplantaris.
随机选取14例掌跖脓疱病患者，检查骨骼受累情况。5例患者（36%）出现骨骼疾病的症状以及临床和影像学体征。4例患者在胸锁关节、第一胸肋关节和/或胸骨柄体关节区域出现侵蚀性和/或硬化性改变，其中2例伴有肋锁韧带骨化。2例患者出现脊柱受累，1例有椎旁骨化，另1例有椎体间盘炎后遗症。3例患者出现外周关节症状，影像学未发现侵蚀，但有关节周围新骨形成。骨骼改变可能并非偶然，似乎构成一种与掌跖脓疱病相关的血清阴性脊柱关节病。
