Calderón-Larrañaga A, Soljak M, Cecil E, Valabhji J, Bell D, Prados Torres A, Majeed A
Department of Microbiology, Preventative Medicine and Public Health, Aragon Health Research Institute, Zaragoza, Spain.
Diabet Med. 2014 Jun;31(6):657-65. doi: 10.1111/dme.12413. Epub 2014 Mar 26.
To determine if hospital admission rates for diabetes complications (acute complications, chronic complications, no complications and hypoglycaemia) were associated with primary care diabetes management.
We performed an observational study in the population in England during the period 2004-2009 (54 741 278 people registered with 8140 general practices). We used multivariable negative binomial regression to model the associations between indirectly standardized hospital admission rates for complications and primary healthcare quality, supply and access indicators, diabetes prevalence and population factors.
In multivariate regression models, increasing deprivation (incidence rate ratio: 1.0154; P < 0.001, 95% CI 1.0141-1.0166) and diabetes prevalence (incidence rate ratio: 1.0956; P < 0.001, 95% CI 1.0677-1.1241) were risk factors for admission, while most healthcare covariates, i.e. a larger practice population (incidence rate ratio 0.9999, P = 0.013, 95% CI 0.9999-0.9999), better patient-perceived urgent and non-urgent access to primary care (incidence rate ratio: 0.9989, P = 0.023; 95% CI 0.9979-0.9998 and incidence rate ratio: 0.9988; P = 0.003, 95% CI 0.9980-0.9996, respectively) and better HbA1c target achievement (incidence rate ratio: 0.9971; P < 0.001, 95% CI 0.9958-0.9984), were protective. Diabetes admissions decreased significantly during the period 2004-2009.
After controlling for population factors, better scheduled primary care access and glycaemic control were associated with lower hospital admission rates across most complications. There is little rationale to restrict primary care-sensitive condition definitions to acute complications. They should be revised to improve the usefulness of hospital admission data as an outcome measure, and to facilitate international comparisons. The risk of emergency hospital admission should be monitored routinely.
确定糖尿病并发症(急性并发症、慢性并发症、无并发症及低血糖症)的住院率是否与初级医疗糖尿病管理相关。
我们对2004年至2009年期间英格兰的人群进行了一项观察性研究(54741278人在8140家全科诊所登记)。我们使用多变量负二项回归模型来分析并发症的间接标准化住院率与初级医疗质量、服务提供和可及性指标、糖尿病患病率及人口因素之间的关联。
在多变量回归模型中,贫困程度增加(发病率比:1.0154;P<0.001,95%可信区间1.0141 - 1.0166)和糖尿病患病率(发病率比:1.0956;P<0.001,95%可信区间1.0677 - 1.1241)是住院的危险因素,而大多数医疗协变量,即规模较大的诊所人群(发病率比0.9999,P = 0.013,95%可信区间0.9999 - 0.9999)、患者感知的初级医疗紧急和非紧急可及性更好(发病率比:0.9989,P = 0.023;95%可信区间0.9979 - 0.9998和发病率比:0.9988;P = 0.003,95%可信区间0.9980 - 0.9996)以及更好地实现糖化血红蛋白目标(发病率比:0.9971;P<0.001,95%可信区间0.9958 - 0.9984)具有保护作用。2004年至2009年期间糖尿病住院人数显著下降。
在控制人口因素后,更好的定期初级医疗可及性和血糖控制与大多数并发症较低的住院率相关。几乎没有理由将初级医疗敏感病症的定义局限于急性并发症。应修订这些定义,以提高住院数据作为一项结局指标的有用性,并便于进行国际比较。应常规监测急诊住院风险。