Clarke Lesa, Fodey Terence L, Crooks Steven R H, Moloney Mary, O'Mahony John, Delahaut Philippe, O'Kennedy Richard, Danaher Martin
Food Safety Department, Teagasc Food Research Centre, Ashtown, Dublin 15, Ireland; School of Biotechnology and National Centre for Sensor Research, Dublin City University, Dublin 9, Ireland.
Veterinary Sciences Division, Agri-Food & Biosciences Institute, Belfast, Northern Ireland, United Kingdom.
Meat Sci. 2014 Jul;97(3):358-74. doi: 10.1016/j.meatsci.2014.01.004. Epub 2014 Jan 22.
Coccidiostats are used in the control of protozoan infections in different food producing animals. They are most widely used as feed additives in intensively reared species such as pigs and poultry to maintain animal health and in some cases enhance feed conversion. However, a number of these drugs are used in the control of infections in beef and lamb production. Coccidiostat residues have been frequently reported in meat and eggs in a number of countries since the late 1990s. This has prompted increased research and surveillance of coccidiostat residues in food. This paper reviews the various coccidiostat agents used in animal production, including their chemical properties, mode of action and activity. Legislation concerning coccidiostats, limits for residues in food, monitoring and occurrence of residues in food is discussed. Methods for residue determination in food, including screening and physicochemical methods are discussed in depth. The paper concludes with a synopsis of the current state of coccidiostat residue analysis and future perspectives.
抗球虫药用于控制不同食用动物的原生动物感染。它们作为饲料添加剂在猪和家禽等集约化养殖的物种中使用最为广泛，以维持动物健康，在某些情况下还能提高饲料转化率。然而，其中一些药物也用于控制牛肉和羊肉生产中的感染。自20世纪90年代末以来，许多国家的肉类和蛋类中频繁报告有抗球虫药残留。这促使人们加强了对食品中抗球虫药残留的研究和监测。本文综述了动物生产中使用的各种抗球虫药，包括它们的化学性质、作用方式和活性。讨论了有关抗球虫药的立法、食品中残留限量、监测以及食品中残留的出现情况。深入讨论了食品中残留量的测定方法，包括筛选方法和物理化学方法。本文最后总结了抗球虫药残留分析的现状和未来展望。
