Anticoccidial activity of natural plants extracts mixture against : An and study.

Coccidiosis, an acute epidemic intestinal disease of poultry, is caused by the parasitic protozoan genus , with being the most pathogenic spp. Novel approaches are required to address the limitations of current treatments for this disease. We investigated the effects of eight plant extracts and essential oils and their mixture on as potential treatments for coccidial infection. The anticoccidial effects of non-toxic concentrations of L. (0.005 mg/mL), L. (0.780 mg/mL), L. (0.390 mg/mL), L. (0.390 mg/mL), Poir (0.050 mg/mL), and L. sp. Pl. (0.050 mg/mL) extracts; Levl. et Vant. (0.010 μL/mL) and (L.) O. Ktze (0.050 μL/mL) essential oils; and their mixture (0.500 mL/mL) on were determined using cell viability assays, flow cytometry, and studies. The eight plant extracts and essential oils and their mixture inhibited sporozoites from invading chicken embryo fibroblast cells . The extract and essential oil mixture improved the feed conversion ratio and body weight gain, reduced fecal oocyst excretion, substantially reduced the mortality of -infected chickens, and reduced -induced cecal damage . The results suggest that the extract and essential oil mixtures inhibit invasion both and , demonstrating their potential as anticoccidial agents.