Galletti Francesco, Cammaroto Giovanni, Galletti Bruno, Quartuccio Natale, Di Mauro Francesca, Baldari Sergio
Department of Otorhinolaryngology, University of Messina, Messina, Italy,
Eur Arch Otorhinolaryngol. 2015 Jun;272(6):1377-82. doi: 10.1007/s00405-014-2938-1. Epub 2014 Feb 18.
We report two cases of malignant external otitis (MEO) evaluated with Technetium-99m((99m)Tc)-labelled sulesomab. Two patients affected by MEO are presented, together with a literature review. Both patients were studied with clinical examination, ear discharge culture, radiological imaging, blood exams, (99m)Tc Sulesomab, and treated with antibiotic therapy. (99m)Tc-Sulesomab would appear to be an useful tool for diagnosis and follow-up of MEO, highlighting the site and extension of the inflammatory process, and evaluating course and treatment efficacy. (99m)Tc-Sulesomab shows promise as a rapid, effective and safe imaging agent for treatment response evaluation and follow-up of patients with MEO. Further studies are warranted to validate the inclusion of (99m)Tc-Sulesomab scan in the imaging follow-up of patients with MEO.
我们报告了两例用锝-99m（99mTc）标记的舒来昔单抗评估的恶性外耳道炎（MEO）病例。本文介绍了两名患有MEO的患者，并进行了文献综述。两名患者均接受了临床检查、耳分泌物培养、放射影像学检查、血液检查、99mTc舒来昔单抗检查，并接受了抗生素治疗。99mTc舒来昔单抗似乎是MEO诊断和随访的有用工具，可突出炎症过程的部位和范围，并评估病程和治疗效果。99mTc舒来昔单抗有望成为一种快速、有效且安全的成像剂，用于评估MEO患者的治疗反应和随访。有必要进行进一步研究，以验证将99mTc舒来昔单抗扫描纳入MEO患者的影像学随访。
