前列腺特异性抗原（PSA）和前列腺酸性磷酸酶（PAP）作为前列腺癌的免疫组化标志物。
PSA and PAP as immunohistochemical markers in prostate cancer.
作者信息
Epstein J I
机构信息
Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland.
出版信息
Urol Clin North Am. 1993 Nov;20(4):757-70.
PMID:7505984
Abstract
This article describes the immunoreactivity of PSA and PAP in non-neoplastic and neoplastic prostate tissue. Listed are examples of cross reactivity of PSA and PAP in non-neoplastic and neoplastic tissue from other organs. The use of PSA and PAP to identify tumors of prostatic origin in different sites is also described. Finally, the diagnostic uses of immunohistochemistry for PSA and PAP in prostate biopsies and for prognostication are discussed.
摘要
本文描述了前列腺特异性抗原（PSA）和前列腺酸性磷酸酶（PAP）在非肿瘤性和肿瘤性前列腺组织中的免疫反应性。列出了PSA和PAP在其他器官的非肿瘤性和肿瘤性组织中的交叉反应实例。还描述了使用PSA和PAP来识别不同部位前列腺来源肿瘤的情况。最后，讨论了免疫组织化学检测PSA和PAP在前列腺活检诊断及预后评估中的应用。
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