Zapara G A, Ratushniak A S, Shtark M B
Zh Vyssh Nerv Deiat Im I P Pavlova. 1988 Jan-Feb;38(1):140-5.
Transmembrane ion currents were studied on limited (pore diameter 6-15 mcm) areas of isolated neurone's soma membrane. The significant differences of the amplitude and correlation of input and output currents of various areas of the cell membrane were observed. The different directions of transmembrane ion currents' local changes were recorded only in the site of action stimulus during the formation of plastic changes of neurone responses. Natural heterogeneity of total ion current of cell membrane, rapid changes of current components values at local influences probably testify to the possibility of selective plasticity of separate neurone areas.
在分离的神经元胞体膜的有限区域(孔径6 - 15微米)上研究跨膜离子电流。观察到细胞膜不同区域的输入和输出电流的幅度及相关性存在显著差异。仅在神经元反应的可塑性变化形成过程中,在动作刺激部位记录到跨膜离子电流局部变化的不同方向。细胞膜总离子电流的天然异质性,以及局部影响时电流成分值的快速变化,可能证明了单个神经元区域存在选择性可塑性的可能性。